apoidea/pubtabnet-html · Datasets at Hugging Face

split stringclasses 1 value	imgid int64 3 549k	html stringlengths 540 86.9k	html_table stringlengths 557 50.4k
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'</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '</tbody>']}}	<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Clinical and laboratory parameters </b> </td> <td> <b> FS <sup> a </sup> = 0 </b> </td> <td> <b> 0 < FS < 1 </b> </td> <td> <b> 1 ≤ FS < 2 </b> </td> <td> <b> FS ≥ 2 </b> </td> </tr> </thead> <tbody> <tr> <td> No. of patients </td> <td> 57 </td> <td> 11 </td> <td> 15 </td> <td> 37 </td> </tr> <tr> <td> Sex </td> <td> 9M/48F </td> <td> 1 M/10 F </td> <td> 0 M/15 F </td> <td> 3 M/34 F </td> </tr> <tr> <td> Age (years) </td> <td> 46 ± 12 </td> <td> 46 ± 11 </td> <td> 54 ± 14 </td> <td> 56 ± 13 </td> </tr> <tr> <td> Baseline biopsy area (mm <sup> 2 </sup> ) </td> <td> 6.1 ± 5.6 </td> <td> 8.3 ± 2.8 </td> <td> 8.6 ± 4.3 </td> <td> 4.7 ± 2.6 </td> </tr> <tr> <td> Cumulative area of three biopsies (mm <sup> 2 </sup> ) </td> <td> 17.1 ± 15.1 </td> <td> 21.8 ± 9.3 </td> <td> 22.6 ± 12.7 </td> <td> 12.9 ± 6.4 </td> </tr> <tr> <td> Findings [No. (%)] </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> Dry eyes </td> <td> 49 (86) </td> <td> 9 (81) </td> <td> 14 (93) </td> <td> 33 (89) </td> </tr> <tr> <td> Xerostomia </td> <td> 45 (79) </td> <td> 7 (63) </td> <td> 14 (93) </td> <td> 35 (94) </td> </tr> <tr> <td> Positive Schirmer's test </td> <td> 24 (42) </td> <td> 4 (36) </td> <td> 9 (60) </td> <td> 18 (51) </td> </tr> <tr> <td> Reduced salivary flow rate </td> <td> 30 (53) </td> <td> 7 (63) </td> <td> 13 (86) </td> <td> 34 (91) </td> </tr> <tr> <td> Antinuclear antibodies </td> <td> 29 (51) </td> <td> 8 (73) </td> <td> 8 (53) </td> <td> 31 (83) </td> </tr> <tr> <td> Ro/SS-A </td> <td> 18 (31) </td> <td> 3 (27) </td> <td> 6 (40) </td> <td> 25 (67) </td> </tr> <tr> <td> La/SS-B </td> <td> 3 (5) </td> <td> 0 </td> <td> 3 (20) </td> <td> 10 (27) </td> </tr> <tr> <td> Rheumatoid factor </td> <td> 27 (47) </td> <td> 5 (45) </td> <td> 7 (46) </td> <td> 33 (89) </td> </tr> <tr> <td> SS according to AECG criteria [No. (%)] </td> <td> 7 (12) </td> <td> 1 (9) </td> <td> 15 (100) </td> <td> 34 (92) </td> </tr> <tr> <td> SS according to clinical re-evaluation [No. (%)] </td> <td> 7 (12) </td> <td> 0 (0) </td> <td> 8 (53) </td> <td> 34 (92) </td> </tr> </tbody> </table> </body> </html>
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'<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '</tbody>']}}	<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Test results and diagnostic accuracy </b> </td> <td> <b> FS <sup> a </sup> = 0 </b> </td> <td> <b> 0 < FS < 1 </b> </td> <td> <b> 1 ≤ FS < 2 </b> </td> <td> <b> FS ≥ 2 </b> </td> <td> <b> Total </b> </td> </tr> </thead> <tbody> <tr> <td> No. of patients </td> <td> 57 </td> <td> 11 </td> <td> 15 </td> <td> 37 </td> <td> 120 </td> </tr> <tr> <td> AECG classification changes </td> <td> 0 </td> <td> 0 </td> <td> 6 (40°%) </td> <td> 1 (3%) </td> <td> 7 </td> </tr> <tr> <td> Baseline sensitivity (95% CI) </td> <td> 85.7%(42.2–97.6) </td> <td> - </td> <td> 100%(62.9–100) </td> <td> 94.1%(80.3–99.1) </td> <td> 93.9%(83.1–98.6) </td> </tr> <tr> <td> Revised sensitivity (95% CI) </td> <td> 85.7%(42.2–97.6) </td> <td> - </td> <td> 100%(62.9–100) </td> <td> 94.1%(80.3–99.1) </td> <td> 93.9%(83.1–98.6) </td> </tr> <tr> <td> Baseline specificity (95% CI) </td> <td> 98%(89.3–99.7) </td> <td> - </td> <td> 0% <sup> b </sup> (0–41.1) </td> <td> 33.3% <sup> b </sup> (5.5–88.4) </td> <td> 84.5%(74.0–92.0) </td> </tr> <tr> <td> Revised specificity (95% CI) </td> <td> 98%(89.3–99.7) </td> <td> - </td> <td> 85.7%(42.2–97.6) </td> <td> 66.7%(11.6–94.5) </td> <td> 94.4%(86.2–98.4) </td> </tr> </tbody> </table> </body> </html>
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<td> Rheumatoid factor-positive ( <i> n </i> ) </td> <td> 25 </td> <td> n.s. </td> <td> 53 </td> <td> <0.0001 </td> <td> 10 </td> </tr> <tr> <td> C-reactive protein (mg/l) </td> <td> 45 ± 9 </td> <td> 0.035 </td> <td> 29 ± 5 </td> <td> n.s. </td> <td> 39 ± 7 </td> </tr> <tr> <td> White blood cell count (× 10 <sup> 9 </sup> /ml) </td> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> Blood </td> <td> 8.7 ± 0.6 </td> <td> 0.038 </td> <td> 7.2 ± 0.3 </td> <td> n.s. </td> <td> 7.1 ± 0.3 </td> </tr> <tr> <td> Synovial fluid </td> <td> 10.8 ± 1.9 </td> <td> n.s. </td> <td> 11.2 ± 2.9 </td> <td> n.s. </td> <td> 13.1 ± 2.8 </td> </tr> </tbody> </table> </body> </html>
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<td> <b> WT </b> </td> </tr> </thead> <tbody> <tr> <td> Naive </td> <td> 1 </td> <td> Thymus </td> <td> 3.2 ± 0.6 (5) </td> <td> 2.2 ± 0.7 (5) </td> </tr> <tr> <td> </td> <td> </td> <td> Spleen </td> <td> 10.1 ± 0.9 (3) * </td> <td> 7.4 ± 0.2 (3) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 6.9 ± 1.1 (5) </td> <td> 5.1 ± 1.1 (5) </td> </tr> <tr> <td> </td> <td> 2 </td> <td> Spleen </td> <td> 14.4 (1) </td> <td> 9.9 (1) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 9.1 ± 0.9 (4) </td> <td> 6.6 ± 0.7 (4) </td> </tr> <tr> <td> </td> <td> 3 </td> <td> Lymph nodes </td> <td> 11.2 (1) </td> <td> 7.0 (1) </td> </tr> <tr> <td> CIA </td> <td> 4 </td> <td> Thymus </td> <td> 3.5 ± 0.9 (3) </td> <td> 4.0 ± 1.6 (3) </td> </tr> <tr> <td> </td> <td> </td> <td> Spleen </td> <td> 11.0 ± 1.3 (2) </td> <td> 7.9 ± 0.7 (2) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 10.2 ± 0.8 (6) </td> <td> 7.7 ± 0.6 (6) </td> </tr> <tr> <td> </td> <td> 5 </td> <td> Spleen </td> <td> 12.1 ± 2.9 (3) </td> <td> 9.2 ± 0.8 (3) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 12.9 ± 1.4 (4) </td> <td> 10.3 ± 1.1 (4) </td> </tr> <tr> <td> </td> <td> 6 </td> <td> Lymph nodes </td> <td> 13.4 ± 0.4 (4) * </td> <td> 9.2 ± 0.7 (4) </td> </tr> </tbody> </table> </body> </html>
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<tr> <td> CD163 sublining layer </td> <td> Semiquantitative </td> </tr> <tr> <td> Intracellular citrullinated peptides </td> <td> Present or absent </td> </tr> <tr> <td> MHC class II–HC gp39 peptide complex, recognized by mAb 12A </td> <td> Present or absent </td> </tr> </tbody> </table> </body> </html>
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font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Essential oil </b> </td> <td> <b> Parent plant </b> </td> <td> <b> Main constituents </b> </td> <td> <b> Manufacturer of the oil </b> </td> <td> <b> References for clinical use </b> </td> </tr> </thead> <tbody> <tr> <td> Eucalyptus </td> <td> <i> Eucalyptus glogulus </i> </td> <td> 1,8 – cineole </td> <td> Sanoflore (France) </td> <td> 11 </td> </tr> <tr> <td> Tea tree </td> <td> <i> Melaleuca alternifolia </i> </td> <td> terpinen-4-ol </td> <td> Sanoflore (France) </td> <td> 12,13 </td> </tr> <tr> <td> True Lavender </td> <td> <i> Lavandula angustifolia </i> </td> <td> linalool </td> <td> Sanoflore (France) </td> <td> 11–13 </td> </tr> <tr> <td> Geranium Bourbon </td> <td> <i> Perargonium asperum </i> </td> <td> geraniol, β-citronellol </td> <td> Sanoflore (France) </td> <td> 11–13 </td> </tr> <tr> <td> Juniper </td> <td> <i> Juniperus communis </i> </td> <td> α-pinene </td> <td> Sanoflore (France) </td> <td> 11–13 </td> </tr> </tbody> </table> </body> </html>
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<b> 94 </b> </td> <td> <b> 100.0 </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Government health department </b> </td> <td> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> </tr> <tr> <td> </td> <td> Full time </td> <td> 25 </td> <td> 83.3 </td> </tr> <tr> <td> </td> <td> Part time </td> <td> 5 </td> <td> 16.7 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 30 </td> <td> 100.0 </td> </tr> <tr> <td> </td> <td> Junior </td> <td> 0 </td> <td> 0.0 </td> </tr> <tr> <td> </td> <td> Mid-career </td> <td> 16 </td> <td> 53.3 </td> </tr> <tr> <td> </td> <td> Senior </td> <td> 14 </td> <td> 46.7 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 30 </td> <td> 100.0 </td> </tr> <tr> <td> <b> Health service </b> </td> <td> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> </tr> <tr> <td> </td> <td> Full time </td> <td> 15 </td> <td> 57.7 </td> </tr> <tr> <td> </td> <td> Part time </td> <td> 11 </td> <td> 42.3 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 26 </td> <td> 100.0 </td> </tr> <tr> <td> </td> <td> Junior </td> <td> 2 </td> <td> 8.3 </td> </tr> <tr> <td> </td> <td> Mid-career </td> <td> 11 </td> <td> 45.8 </td> </tr> <tr> <td> </td> <td> Senior </td> <td> 11 </td> <td> 45.8 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 24 </td> <td> 100.0 </td> </tr> <tr> <td> <b> Private company </b> </td> <td> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> </tr> <tr> <td> </td> <td> Full time </td> <td> 7 </td> <td> 100.0 </td> </tr> <tr> <td> </td> <td> Part time </td> <td> 0 </td> <td> 0.0 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 7 </td> <td> 100.0 </td> </tr> <tr> <td> </td> <td> Junior </td> <td> 0 </td> <td> 0.0 </td> </tr> <tr> <td> </td> <td> Mid-career </td> <td> 3 </td> <td> 50.0 </td> </tr> <tr> <td> </td> <td> Senior </td> <td> 3 </td> <td> 50.0 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 6 </td> <td> 100.0 </td> </tr> <tr> <td> <b> Self-employed </b> </td> <td> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> </tr> <tr> <td> </td> <td> Full time </td> <td> 3 </td> <td> 23.1 </td> </tr> <tr> <td> </td> <td> Part time </td> <td> 10 </td> <td> 76.9 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 13 </td> <td> 100.0 </td> </tr> <tr> <td> </td> <td> Junior </td> <td> 0 </td> <td> 0.0 </td> </tr> <tr> <td> </td> <td> Mid-career </td> <td> 1 </td> <td> 9.1 </td> </tr> <tr> <td> </td> <td> Senior </td> <td> 10 </td> <td> 90.9 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 11 </td> <td> 100.0 </td> </tr> </tbody> </table> </body> </html>
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</td> <td colspan="2"> <b> 3 <sup> rd </sup> choice </b> </td> </tr> <tr> <td> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Competitive funding bodies </b> </td> <td> 90 </td> <td> 60.8 </td> <td> 45 </td> <td> 30.4 </td> <td> 29 </td> <td> 19.6 </td> </tr> <tr> <td> <b> Government departments </b> </td> <td> 52 </td> <td> 35.1 </td> <td> 64 </td> <td> 43.2 </td> <td> 26 </td> <td> 17.6 </td> </tr> <tr> <td> <b> Universities and institutes </b> </td> <td> 2 </td> <td> 1.4 </td> <td> 4 </td> <td> 2.7 </td> <td> 5 </td> <td> 3.4 </td> </tr> <tr> <td> <b> Health foundations </b> </td> <td> 1 </td> <td> 0.7 </td> <td> 6 </td> <td> 4.1 </td> <td> 7 </td> <td> 4.7 </td> </tr> <tr> <td> <b> Local services </b> </td> <td> 1 </td> <td> 0.7 </td> <td> 1 </td> <td> 0.7 </td> <td> 1 </td> <td> 0.7 </td> </tr> <tr> <td> <b> Professional bodies </b> </td> <td> 1 </td> <td> 0.7 </td> <td> 1 </td> <td> 0.7 </td> <td> 0 </td> <td> 0.0 </td> </tr> <tr> <td> <b> Non-government organisations </b> </td> <td> 1 </td> <td> 0.7 </td> <td> 0 </td> <td> 0.0 </td> <td> 4 </td> <td> 2.7 </td> </tr> <tr> <td> <b> Other </b> </td> <td> 0 </td> <td> 0.0 </td> <td> 2 </td> <td> 1.4 </td> <td> 2 </td> <td> 1.4 </td> </tr> <tr> <td> <b> Philanthropic trusts </b> </td> <td> 0 </td> <td> 0.0 </td> <td> 2 </td> <td> 1.4 </td> <td> 2 </td> <td> 1.4 </td> </tr> <tr> <td> <b> Drug companies </b> </td> <td> 0 </td> <td> 0.0 </td> <td> 1 </td> <td> 0.7 </td> <td> 1 </td> <td> 0.7 </td> </tr> <tr> <td> <b> Private companies </b> </td> <td> 0 </td> <td> 0.0 </td> <td> 1 </td> <td> 0.7 </td> <td> 1 </td> <td> 0.7 </td> </tr> <tr> <td> <b> Insurers </b> </td> <td> 0 </td> <td> 0.0 </td> <td> 0 </td> <td> 0.0 </td> <td> 2 </td> <td> 1.4 </td> </tr> </tbody> </table> </body> </html>
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</tr> <tr> <td> <b> Book chapters </b> </td> <td> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> </tr> <tr> <td> </td> <td> 1 </td> <td> 22 </td> <td> 59.5 </td> </tr> <tr> <td> </td> <td> 2 </td> <td> 9 </td> <td> 24.3 </td> </tr> <tr> <td> </td> <td> 3 </td> <td> 2 </td> <td> 5.4 </td> </tr> <tr> <td> </td> <td> 4 or more </td> <td> 4 </td> <td> 10.8 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 37 </td> <td> 100.0 </td> </tr> <tr> <td> <b> Commissioned reports </b> </td> <td> </td> <td> <b> Frequency </b> </td> <td> <b> Percentage </b> </td> </tr> <tr> <td> </td> <td> 1 </td> <td> 20 </td> <td> 25.0 </td> </tr> <tr> <td> </td> <td> 2 </td> <td> 22 </td> <td> 27.5 </td> </tr> <tr> <td> </td> <td> 3 </td> <td> 13 </td> <td> 16.3 </td> </tr> <tr> <td> </td> <td> 4 or more </td> <td> 25 </td> <td> 31.3 </td> </tr> <tr> <td> </td> <td> Total </td> <td> 80 </td> <td> 100.0 </td> </tr> <tr> <td> <b> Published conference proceedings </b> </td> <td> </td> <td> <b> 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abscess in the past </td> <td> 3 </td> <td> 0.74 </td> <td> 0.87 </td> </tr> <tr> <td colspan="2"> Infection with other catheter material in the past </td> <td> 16 </td> <td> 0.17 </td> <td> 0.26 </td> </tr> <tr> <td colspan="2"> Easy perspiration <sup> 1 </sup> </td> <td> 11 </td> <td> 2.33 </td> <td> 0.32 </td> </tr> <tr> <td> </td> <td> Any of the three afore mentioned factors </td> <td> 14 </td> <td> 1.64 </td> <td> 0.43 </td> </tr> <tr> <td colspan="2"> Localization of the catheter ("clean" vs. "dirty") <sup> 2 </sup> </td> <td> 8 </td> <td> 0.38 </td> <td> 0.37 </td> </tr> <tr> <td colspan="2"> Puncture site in the groin </td> <td> Not removed </td> <td> 3.39 </td> <td> 0.004 </td> </tr> <tr> <td colspan="2"> Epidural catheter vs. peripheral nerve catheter </td> <td> 17 </td> <td> 1.24 </td> <td> 0.11 </td> </tr> <tr> <td colspan="2"> Disinfection technique (wiping versus spraying) </td> <td> 9 </td> <td> 1.88 </td> <td> 0.50 </td> </tr> <tr> <td colspan="2"> Number of attempts during catheter placement </td> <td> 10 </td> <td> 1.49 </td> <td> 0.38 </td> </tr> <tr> <td colspan="2"> Fixation technique (tunneling versus suturing) </td> <td> 1 </td> <td> 0.97 </td> <td> 0.97 </td> </tr> <tr> <td colspan="2"> Intraoperative corticosteroid medication </td> <td> 4 </td> <td> 1.40 </td> <td> 0.75 </td> </tr> <tr> <td> Intraoperative single shot antibiotic administration </td> <td> </td> <td> 6 </td> <td> 2.34 </td> <td> 0.47 </td> </tr> <tr> <td> Postoperative antibiotic therapy (at least 3 days or until removal of the catheter) </td> <td> </td> <td> Not removed </td> <td> 0.41 </td> <td> 0.05 </td> </tr> <tr> <td> </td> <td> Perioperative antibiotic therapy (intra- & postoperative) </td> <td> 23 </td> <td> 0.43 </td> <td> 0.09 </td> </tr> <tr> <td colspan="2"> Duration of catheter use (per day) </td> <td> 21 </td> <td> 1.17 </td> <td> 0.16 </td> </tr> <tr> <td colspan="2"> Accidental disconnection of the catheter </td> <td> 22 </td> <td> 0.78 </td> <td> 0.19 </td> </tr> <tr> <td> Accidental removal of the catheter dressing (n =) </td> <td> </td> <td> 15 </td> <td> 0.50 </td> <td> 0.37 </td> </tr> <tr> <td> Intentioned replacements of the catheter dressing (n =) </td> <td> </td> <td> 13 </td> <td> 0.83 </td> <td> 0.31 </td> </tr> <tr> <td> </td> <td> Removal of the catheter dressing (intentionally or unintentionally; n =) </td> <td> Not removed </td> <td> 2.12 </td> <td> 0.001 </td> </tr> </tbody> </table> </body> </html>
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<underline> ≥15 CFU </underline> </td> </tr> <tr> <td> <underline> Normal skin flora </underline> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> Coagulase negative staphylococci </td> <td> n = 40 (60.6%) </td> <td> 10 </td> <td> 30 </td> </tr> <tr> <td> Bacillus species </td> <td> n = 9 (13.6%) </td> <td> 5 </td> <td> 4 </td> </tr> <tr> <td> Enterococcus species </td> <td> n = 3 (4.5%) </td> <td> 2 </td> <td> 1 </td> </tr> <tr> <td> <underline> Optional pathogenic </underline> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> Escherichia coli </td> <td> n = 5 (7.8%) </td> <td> 5 </td> <td> 0 </td> </tr> <tr> <td> Enterobacter species </td> <td> n = 3 (4.5%) </td> <td> 2 </td> <td> 1 </td> </tr> <tr> <td> Klebsiella species </td> <td> n = 3 (4.5%) </td> <td> 3 </td> <td> 0 </td> </tr> <tr> <td> Morganella morganii </td> <td> n = 1 (1.5%) </td> <td> 1 </td> <td> 0 </td> </tr> <tr> <td> Nonfermenter species </td> <td> n = 1 (1.5%) </td> <td> 1 </td> <td> 0 </td> </tr> <tr> <td> Pseudomonas aeruginosa </td> <td> n = 1 (1.5%) </td> <td> 0 </td> <td> 1 </td> </tr> </tbody> </table> </body> </html>
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width="100%"> <thead> <tr> <td> <b> Localization </b> </td> <td> <b> Total number of catheters </b> </td> <td> <b> Duration of catheter use (days) </b> </td> <td> <b> Not colonized n (%) </b> </td> <td> <b> Colonized n (%) </b> </td> <td> <b> Colonized <i> and </i> local infectious signs; n (%) </b> </td> </tr> </thead> <tbody> <tr> <td> Epidural catheter (C6/7 - T2/3) </td> <td> 29 </td> <td> 6 (5 / 8) </td> <td> 29 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Epidural catheter (T3/4 - T 12/L1) </td> <td> 59 </td> <td> 4 (3 / 6) </td> <td> 51 (86.4%) </td> <td> 8 (13.6%) </td> <td> 4 (6.8%) </td> </tr> <tr> <td> Epidural catheter (L1/2 - L4/5) </td> <td> 8 </td> <td> 4 (3 / 6) </td> <td> 7 (87.5%) </td> <td> 1 (12.5%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Paravertebral catheter (level T3 - T8) </td> <td> 4 </td> <td> 1 (1 / 3) </td> <td> 4 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Psoas compartment </td> <td> 5 </td> <td> 4 (3 / 4) </td> <td> 4 (80%) </td> <td> 1 (20%) </td> <td> 1 (20%) </td> </tr> <tr> <td> Posterior sciatic (gluteal) </td> <td> 1 </td> <td> 2 </td> <td> 1 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Distal sciatic (popliteal) </td> <td> 1 </td> <td> 2 </td> <td> 1 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Anterior sciatic (proximal) </td> <td> 7 </td> <td> 2 (1 / 3) </td> <td> 4 (57.1%) </td> <td> 3 (42.9%) </td> <td> 1 (14.3%) </td> </tr> <tr> <td> Femoral nerve </td> <td> 68 </td> <td> 3 (1 / 3) </td> <td> 50 (73.5%) </td> <td> 18 (26.5%) </td> <td> 10 (14.7%) </td> </tr> <tr> <td> Interscalene plexus </td> <td> 9 </td> <td> 2 (1 / 3) </td> <td> 8 (88.9%) </td> <td> 1 (11.1%) </td> <td> 1 (11.1%) </td> </tr> <tr> <td> Infraclavicular plexus </td> <td> 5 </td> <td> 3 (2 / 6) </td> <td> 4 (80%) </td> <td> 1 (20%) </td> <td> 1 (20%) </td> </tr> <tr> <td> Axillary plexus </td> <td> 2 </td> <td> 3 (1 / 4) </td> <td> 2 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Total </td> <td> 198 </td> <td> 3 (2 / 5) </td> <td> 151 (83.3%) </td> <td> 33 (16.7%) </td> <td> 18 (9.1%) </td> </tr> </tbody> </table> </body> </html>
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font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Case </b> </td> <td> <b> Nucleotide Substitution <sup> a </sup> </b> </td> <td> <b> Amino acid change </b> </td> <td> <b> Age </b> </td> <td> <b> Sex </b> </td> <td> <b> MSI Status <sup> b,c </sup> </b> </td> <td> <b> <i> KRAS </i> Mutation <sup> c </sup> </b> </td> <td> <b> Tumour site </b> </td> <td> <b> Tumour type </b> </td> <td> <b> IM <sup> d </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> 28 </td> <td> A3140G </td> <td> H1047R </td> <td> 37 </td> <td> M </td> <td> Stable </td> <td> - </td> <td> Body </td> <td> Intestinal </td> <td> 0 </td> </tr> <tr> <td> 100 </td> <td> G1633A </td> <td> E545K </td> <td> 79 </td> <td> F </td> <td> High </td> <td> - </td> <td> Antrum </td> <td> Intestinal </td> <td> 1 </td> </tr> <tr> <td> 240 </td> <td> G1624A </td> <td> E542K </td> <td> 74 </td> <td> M </td> <td> High </td> <td> G12D </td> <td> Antrum </td> <td> Intestinal </td> <td> 1 </td> </tr> <tr> <td> 310 </td> <td> A3140G </td> <td> H1047R </td> <td> 72 </td> <td> F </td> <td> High </td> <td> G13D </td> <td> Antrum </td> <td> Intestinal </td> <td> 1 </td> </tr> </tbody> </table> </body> </html>
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</td> <td> </td> </tr> <tr> <td> G1 </td> <td> 5 (3) </td> </tr> <tr> <td> G2 </td> <td> 53 (29) </td> </tr> <tr> <td> G3 </td> <td> 96 (53) </td> </tr> <tr> <td> Unknown </td> <td> 26 (14) </td> </tr> <tr> <td> Concomitant radiotherapy, n (%) </td> <td> </td> </tr> <tr> <td> No </td> <td> 114 (63) </td> </tr> <tr> <td> Yes </td> <td> 66 (37) </td> </tr> </tbody> </table> </body> </html>
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and < 65, no RT ( <i> n = 64 </i> ) </td> <td> 92% </td> <td> 8% </td> <td> </td> <td> 67% </td> <td> 33% </td> <td> </td> <td> 59% </td> <td> 41% </td> <td> </td> </tr> <tr> <td> ≥ 65, no RT ( <i> n = 50 </i> ) </td> <td> 92% </td> <td> 8% </td> <td> </td> <td> 76% </td> <td> 24% </td> <td> </td> <td> 72% </td> <td> 28% </td> <td> </td> </tr> <tr> <td> >60 and < 65, RT ( <i> n = 36 </i> ) </td> <td> 75% </td> <td> 25% </td> <td> </td> <td> 81% </td> <td> 19% </td> <td> </td> <td> 67% </td> <td> 33% </td> <td> </td> </tr> <tr> <td> ≥ 65, RT ( <i> n = 30 </i> ) </td> <td> 53% </td> <td> 47% </td> <td> </td> <td> 80% </td> <td> 20% </td> <td> </td> <td> 43% </td> <td> 57% </td> <td> </td> </tr> </tbody> </table> </body> </html>
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</head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Variable </b> </td> <td colspan="3"> <b> Age </b> </td> <td colspan="3"> <b> Radiotherapy </b> </td> </tr> <tr> <td> </td> <td> <b> >60 and < 65 ( <i> n = 100 </i> ) </b> </td> <td> <b> ≥ 65 ( <i> n = 80 </i> ) </b> </td> <td> <b> P <sup> § </sup> </b> </td> <td> <b> No* ( <i> n = 114 </i> ) </b> </td> <td> <b> Yes ( <i> n = 66 </i> ) </b> </td> <td> <b> P <sup> § </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> N. of cycles administered, no. (%) </td> <td> </td> <td> </td> <td> 0.42 </td> <td> </td> <td> </td> <td> 0.01 </td> </tr> <tr> <td> 6 cycles </td> <td> 81 (81) </td> <td> 61 (76) </td> <td> </td> <td> 84 (74) </td> <td> 58 (88) </td> <td> </td> </tr> <tr> <td> 5 cycles </td> <td> 5 (5) </td> <td> 4 (5) </td> <td> </td> <td> 4 (3) </td> <td> 5 (8) </td> <td> </td> </tr> <tr> <td> 4 cycles </td> <td> 4 (4) </td> <td> 4 (5) </td> <td> </td> <td> 6 (5) </td> <td> 2 (3) </td> <td> </td> </tr> <tr> <td> 3 cycles </td> <td> 5 (5) </td> <td> 6 (8) </td> <td> </td> <td> 10 (9) </td> <td> 1 (1) </td> <td> </td> </tr> <tr> <td> 2 cycles </td> <td> 4 (4) </td> <td> 4 (5) </td> <td> </td> <td> 8 (7) </td> <td> 0 </td> <td> </td> </tr> <tr> <td> 1 cycle </td> <td> 1 (1) </td> <td> 1 (1) </td> <td> </td> <td> 2 (2) </td> <td> 0 </td> <td> </td> </tr> <tr> <td> N. of day 8 omitted, no. (%) </td> <td> </td> <td> </td> <td> 0.37 </td> <td> </td> <td> </td> <td> 0.86 </td> </tr> <tr> <td> 0 </td> <td> 69 (69) </td> <td> 51 (64) </td> <td> </td> <td> 77 (68) </td> <td> 43 (65) </td> <td> </td> </tr> <tr> <td> 1 </td> <td> 23 (23) </td> <td> 18 (22) </td> <td> </td> <td> 24 (21) </td> <td> 17 (26) </td> <td> </td> </tr> <tr> <td> 2 </td> <td> 5 (5) </td> <td> 8 (10) </td> <td> </td> <td> 9 (8) </td> <td> 4 (6) </td> <td> </td> </tr> <tr> <td> 3 </td> <td> 3 (3) </td> <td> 3 (4) </td> <td> </td> <td> 4 (3) </td> <td> 2 (3) </td> <td> </td> </tr> <tr> <td> Rate of cycles at reduced dose, no. (%) </td> <td> </td> <td> </td> <td> 0.54 </td> <td> </td> <td> </td> <td> 0.83 </td> </tr> <tr> <td> ≤ 25% </td> <td> 86 (86) </td> <td> 66 (82) </td> <td> </td> <td> 97 (85) </td> <td> 55 (83) </td> <td> </td> </tr> <tr> <td> >25% </td> <td> 14 (14) </td> <td> 14 (18) </td> <td> </td> <td> 17 (15) </td> <td> 11 (17) </td> <td> </td> </tr> <tr> <td> Actual/planned duration, no. (%) </td> <td> </td> <td> </td> <td> 0.59 </td> <td> </td> <td> </td> <td> 0.05 </td> </tr> <tr> <td> ≤ 1.25 </td> <td> 99 (99) </td> <td> 78 (98) </td> <td> </td> <td> 114 (100) </td> <td> 63 (95) </td> <td> </td> </tr> <tr> <td> >1.25 </td> <td> 1 (1) </td> <td> 2 (2) </td> <td> </td> <td> 0 </td> <td> 3 (5) </td> <td> </td> </tr> <tr> <td> G-CSF utilization, no. (%) </td> <td> </td> <td> </td> <td> 0.12 </td> <td> </td> <td> <.0001 </td> <td> </td> </tr> <tr> <td> No </td> <td> 91 (91) </td> <td> 66 (82) </td> <td> </td> <td> 109 (96) </td> <td> 48 (73) </td> <td> </td> </tr> <tr> <td> Yes </td> <td> 9 (9) </td> <td> 14 (18) </td> <td> </td> <td> 5 (4) </td> <td> 18 (27) </td> <td> </td> </tr> <tr> <td> Treatment discontinuation, no. (%) </td> <td> </td> <td> </td> <td> 0.52 </td> <td> </td> <td> </td> <td> 0.10 </td> </tr> <tr> <td> protocol completion </td> <td> 81 (81) </td> <td> 61 (76) </td> <td> </td> <td> 84 (74) </td> <td> 58 (88) </td> <td> </td> </tr> <tr> <td> patient's refusal </td> <td> 6 (6) </td> <td> 9 (11) </td> <td> </td> <td> 12 (11) </td> <td> 3 (4) </td> <td> </td> </tr> <tr> <td> treatment toxicity </td> <td> 11 (11) </td> <td> 7 (9) </td> <td> </td> <td> 13 (11) </td> <td> 5 (8) </td> <td> </td> </tr> <tr> <td> other </td> <td> 2 (2) </td> <td> 3 (4) </td> <td> </td> <td> 5 (4) </td> <td> 0 </td> <td> </td> </tr> <tr> <td> Low compliance <sup> † </sup> , no. (%) </td> <td> </td> <td> </td> <td> 0.02 </td> <td> </td> <td> </td> <td> 0.88 </td> </tr> <tr> <td> No </td> <td> 61 (61) </td> <td> 34 (42) </td> <td> </td> <td> 61 (54) </td> <td> 34 (52) </td> <td> </td> </tr> <tr> <td> yes </td> <td> 39 (39) </td> <td> 46 (58) </td> <td> </td> <td> 53 (46) </td> <td> 32 (48) </td> <td> </td> </tr> </tbody> </table> </body> </html>
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font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Comparison </b> </td> <td colspan="2"> <b> Evolutionary Rate obtained from closely related species </b> </td> <td colspan="2"> <b> Evolutionary Rate obtained from <i> S. cerevisiae </i> - <i> C. elegans </i> </b> </td> </tr> <tr> <td> </td> <td> <b> <i> S. cerevisiae </i> </b> </td> <td> <b> <i> C. elegans </i> </b> </td> <td> <b> <i> S. cerevisiae </i> </b> </td> <td> <b> <i> C. elegans </i> </b> </td> </tr> </thead> <tbody> <tr> <td> Nr. of Interactions </td> <td> <b> -0.11 </b> </td> <td> <b> -0.13 </b> </td> <td> <b> -0.20 </b> </td> <td> <b> -0.10 </b> </td> </tr> <tr> <td> 2.5-percentile </td> <td> -0.20 </td> <td> -0.23 </td> <td> -0.26 </td> <td> -0.19 </td> </tr> <tr> <td> 97.5-percentile </td> <td> -0.02 </td> <td> -0.04 </td> <td> -0.14 </td> <td> -0.03 </td> </tr> <tr> <td> Expression </td> <td> <b> -0.33 </b> </td> <td> <b> -0.44 </b> </td> <td> <b> -0.25 </b> </td> <td> <b> -0.42 </b> </td> </tr> <tr> <td> 2.5-percentile </td> <td> -0.41 </td> <td> -0.50 </td> <td> -0.32 </td> <td> -0.47 </td> </tr> <tr> <td> 97.5-percentile </td> <td> -0.24 </td> <td> -0.36 </td> <td> -0.19 </td> <td> -0.37 </td> </tr> </tbody> </table> </body> </html>
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Inflammatory bowel disease (yes / no) </td> <td> 0 / 45 </td> <td> 16 / 11 </td> </tr> <tr> <td> Total serum bilirubin (median, range in μmol/l) </td> <td> 10 (4–98) </td> <td> 15 (6–37) </td> </tr> <tr> <td> Serum albumin (median, range in g/l) </td> <td> 42 (31–48) </td> <td> 42 (33–47) </td> </tr> <tr> <td> Prothrombin time (median, range in sec.) </td> <td> 12 (10–18) </td> <td> 13 (11–16) </td> </tr> <tr> <td> Serum ALT activity (median, range in U/l) </td> <td> 43 (17–484) </td> <td> 35 (10–662) </td> </tr> <tr> <td> Serum AST activity (median, range in U/l) </td> <td> 37 (21–241) </td> <td> 31 (18–338) </td> </tr> <tr> <td> Serum Alkaline Phosphatase (median, range in U/l) </td> <td> 154 (68–441) </td> <td> 147 (53–1141) </td> </tr> </tbody> </table> </body> </html>
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F33D4.3 </td> <td> <i> flp-13 </i> </td> <td> neuropeptide </td> <td> <b> I5 </b> </td> <td> ASE, ASG, ASK, BAG, DD, M3, M5, head neurons [67] </td> </tr> <tr> <td> 17 </td> <td> C11D2.6 </td> <td> <i> nca-1 </i> </td> <td> Ca <sup> ++ </sup> channel </td> <td> <b> DA </b> </td> <td> DB, VA, VB, head/tail neurons </td> </tr> <tr> <td> 56 </td> <td> F09C3.2 </td> <td> </td> <td> phosphatase </td> <td> <b> DA </b> </td> <td> VA, VB, VD, DB, intestine, hypodermis </td> </tr> <tr> <td> 98 </td> <td> T19C4.5 </td> <td> </td> <td> novel </td> <td> </td> <td> no GFP </td> </tr> <tr> <td> 161 </td> <td> T23D8.2 </td> <td> <i> tsp-7 </i> </td> <td> tetraspanin </td> <td> <b> DA </b> </td> <td> all VNC motor neurons, head/tail neurons, touch neurons </td> </tr> <tr> <td> 165 </td> <td> CC4.2 </td> <td> <i> nlp-15 </i> </td> <td> neuropeptide </td> <td> </td> <td> DD, head/tail neurons, body muscles, pharyngeal muscle [105] </td> </tr> <tr> <td> 210 </td> <td> F29G6.2 </td> <td> </td> <td> novel </td> <td> <b> DA </b> </td> <td> DB, touch neurons, pharyngeal neurons, head neurons </td> </tr> <tr> <td> 215 </td> <td> F39G3.8 </td> <td> <i> tig-2 </i> </td> <td> TGF-β </td> <td> <b> DA </b> </td> <td> VA, VB, DB, body wall muscle, touch neurons, pharyngeal muscle </td> </tr> <tr> <td> 233 </td> <td> F55C12.4 </td> <td> </td> <td> novel </td> <td> <b> DA </b> </td> <td> VB, DB, DD, AS, VD </td> </tr> <tr> <td> 234 </td> <td> E03D2.2 </td> <td> <i> nlp-9 </i> </td> <td> neuropeptide </td> <td> </td> <td> VA, intestine, head neurons [105] </td> </tr> <tr> <td> 239 </td> <td> ZC21.2 </td> <td> <i> trp-1 </i> </td> <td> Ca <sup> ++ </sup> channel </td> <td> <b> DA </b> </td> <td> DB, VA, VB </td> </tr> <tr> <td> 254 </td> <td> Y47D3B.2A </td> <td> <i> nlp-21 </i> </td> <td> neuropeptide </td> <td> <b> DA </b> </td> <td> DB, VA, VB, AS, body muscle, head neurons, intestine [72] </td> </tr> <tr> <td> 329 </td> <td> F36A2.4 </td> <td> <i> twk-30 </i> </td> <td> K <sup> + </sup> channel </td> <td> <b> DA </b> </td> <td> all VNC motor neurons [106] </td> </tr> <tr> <td> 377 </td> <td> C18H9.7 </td> <td> <i> rpy-1 </i> </td> <td> rapsyn </td> <td> <b> DA </b> </td> <td> VD, AS, VB, DB, body muscles </td> </tr> <tr> <td> 593 </td> <td> F43C9.4a </td> <td> <i> mig-13 </i> </td> <td> CUB domain </td> <td> <b> DA </b> </td> <td> DB, ant. VNC motor neurons, pharyngeal/intestinal valves, hypodermis [107] </td> </tr> <tr> <td> 782 </td> <td> T05C12.2 </td> <td> <i> acr-14 </i> </td> <td> nAChR </td> <td> <b> DA </b> </td> <td> VB, AS, DB, DD, HSN, VC4 & 5, AIY, head neurons, muscles, intestine </td> </tr> <tr> <td> 788 </td> <td> T27A1.6 </td> <td> <i> mab-9 </i> </td> <td> transcrip. factor </td> <td> <b> DA </b> </td> <td> DD, DB, VD, AS </td> </tr> <tr> <td> 877 </td> <td> K02E10.8 </td> <td> <i> syg-1 </i> </td> <td> Ig Domain </td> <td> <b> DA </b> </td> <td> VA, HSN and other neurons </td> </tr> </tbody> </table> </body> </html>
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<td> F57F5.5 </td> <td> <i> pkc-1 </i> </td> <td> 743 </td> <td> Serine/threonine protein kinase </td> </tr> <tr> <td> F17C8.1 </td> <td> <i> acy-1 </i> </td> <td> 884 </td> <td> Adenylyl cyclase </td> </tr> <tr> <td> R07E4.6 </td> <td> <i> kin-2 </i> </td> <td> 467 </td> <td> cAMP-dependent protein kinase types I and II, regulatory subunit </td> </tr> <tr> <td> <b> <i> Present (EGs) </i> </b> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> Y69A2AR.1 </td> <td> <i> ric-8 </i> </td> <td> </td> <td> Signaling protein RIC-8/synembryn (regulates neurotransmitter secretion) </td> </tr> <tr> <td> C16C2.2a </td> <td> <i> eat-16 </i> </td> <td> </td> <td> G protein signaling regulators </td> </tr> <tr> <td> B0348.4a </td> <td> <i> egl-8 </i> </td> <td> </td> <td> Phospholipase C </td> </tr> <tr> <td> F52A8.2 </td> <td> <i> gpb-2 </i> </td> <td> </td> <td> G-protein beta subunit </td> </tr> <tr> <td> C26C6.2 </td> <td> <i> goa-1 </i> </td> <td> </td> <td> G-protein alpha subunit (small G protein superfamily) </td> </tr> <tr> <td> ZK542.2a </td> <td> <i> unc-13 </i> </td> <td> </td> <td> Neurotransmitter release regulator, UNC-13 </td> </tr> <tr> <td> C09E10.2a </td> <td> <i> dgk-1 </i> </td> <td> </td> <td> Diacylglycerol kinase </td> </tr> <tr> <td> R06A10.2 </td> <td> <i> gsa-1 </i> </td> <td> </td> <td> G protein subunit Galphas, small G protein superfamily </td> </tr> </tbody> </table> </body> </html>
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charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Total gene pairs sharing one regulator </b> </td> <td> <b> Gene pairs sharing one regulator and both are in the same deacetylation partition group </b> </td> <td> <b> Threshold for correlations </b> </td> <td> <b> Number of gene pairs sharing one regulator above the threshold </b> </td> <td> <b> Number of gene pairs sharing one regulator and both are in the same deacetylation partition group above the threshold </b> </td> <td> <b> P-values based on the hypergeometric tests </b> </td> </tr> </thead> <tbody> <tr> <td> 24,833 </td> <td> 141 </td> <td> 0.5 </td> <td> 4,676 </td> <td> 80 </td> <td> 3.43e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.6 </td> <td> 2,925 </td> <td> 54 </td> <td> 2.37e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.7 </td> <td> 1,519 </td> <td> 45 </td> <td> 2.24e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.8 </td> <td> 422 </td> <td> 20 </td> <td> 2.92e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.9 </td> <td> 30 </td> <td> 3 </td> <td> 0.0000243 </td> </tr> <tr> <td> Total gene pairs sharing one regulator </td> <td> Gene pairs sharing one regulator and they belong to neighboring deacetylation partition groups </td> <td> Threshold for correlations </td> <td> Number of gene pairs sharing one regulator above the threshold </td> <td> Number of gene pairs sharing one regulator and they belong to neighboring deacetylation partition groups above the threshold </td> <td> P-values based on the hypergeometric tests </td> </tr> <tr> <td> 24,833 </td> <td> 46 </td> <td> 0.5 </td> <td> 4,676 </td> <td> 12 </td> <td> 0.0784 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.6 </td> <td> 2,925 </td> <td> 8 </td> <td> 0.0853 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.7 </td> <td> 1,519 </td> <td> 8 </td> <td> 0.00165 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.8 </td> <td> 422 </td> <td> 2 </td> <td> 0.0432 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.9 </td> <td> 30 </td> <td> 0 </td> <td> 0.0541 </td> </tr> </tbody> </table> </body> </html>
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<b> Sequence (5'-3') </b> </td> </tr> </thead> <tbody> <tr> <td> HGF1 </td> <td> 6 </td> <td> CATGAGAAGTATGACAACAGCCTC </td> </tr> <tr> <td> HGF2 </td> <td> 8 </td> <td> TGGTCTCCTCTGACTTCAAC </td> </tr> <tr> <td> HGR1 </td> <td> 9 </td> <td> GTTGCTGTAGCCAAATTCGTTGTC </td> </tr> <tr> <td> HGR2 </td> <td> 9 </td> <td> CTGTAGCCAAATTCGTTGTC </td> </tr> <tr> <td> HSF1 </td> <td> 4 </td> <td> CTACACTCTATGTGCGCAATCG </td> </tr> <tr> <td> HSF2 </td> <td> 1A </td> <td> TAGCAGTGTAGGTGGTTAGCAG </td> </tr> <tr> <td> HSF3 </td> <td> 1B </td> <td> GGGTCTAATTGACTTGAGAATGTG </td> </tr> <tr> <td> HSF4 </td> <td> 4 </td> <td> TTTTTGCATATACCCGCATAG </td> </tr> <tr> <td> HSF5 </td> <td> 1A-3 </td> <td> TCCTTCCTAGCAAGGGATG </td> </tr> <tr> <td> HSF6 </td> <td> 1B-3 </td> <td> AAAAAATTAAGCTGAAATGGATG </td> </tr> <tr> <td> HSR1 </td> <td> 6 </td> <td> TTTGGCTGCTAGTGTGACGTTG </td> </tr> <tr> <td> HSR2 </td> <td> 4 </td> <td> CTGATGCAAAGTATGAGCACAG </td> </tr> <tr> <td> HSR3 </td> <td> 4 </td> <td> CATTCCAGGCCCAGAGGAAAG </td> </tr> <tr> <td> HSR4 </td> <td> 5 </td> <td> CCCATATTACAATTCCAGAAG </td> </tr> <tr> <td> HSR5 </td> <td> 3 </td> <td> AAGTCTGCTTTCAAAATCCAG </td> </tr> <tr> <td> MGF </td> <td> 3 </td> <td> GTGGAGTCTACTGGTGTCTTC </td> </tr> <tr> <td> MGR </td> <td> 5 </td> <td> GTGGCAGTGATGGCATGGAC </td> </tr> <tr> <td> MSF1 </td> <td> 4 </td> <td> GATGCTATGAGTTTAGCACAACG </td> </tr> <tr> <td> MSF2 </td> <td> 1 </td> <td> ATGATGGAGATGCGAGTGGTAG </td> </tr> <tr> <td> MSR1 </td> <td> 5 </td> <td> CATCAGATGTCTCCTTACATGTC </td> </tr> <tr> <td> MSR2 </td> <td> 3 </td> <td> TGTGGTCTGTTTAGTATTAGATGC </td> </tr> <tr> <td> MSR3 </td> <td> 3 </td> <td> TTCCTTCTTACACACTGTGGTC </td> </tr> </tbody> </table> </body> </html>
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characteristics </b> </td> <td> <b> Value </b> </td> <td> <b> N </b> </td> </tr> </thead> <tbody> <tr> <td> Age (years) </td> <td> mean (SD) </td> <td> 78.5 (7.2) </td> <td> 77 </td> </tr> <tr> <td> </td> <td> range </td> <td> 64–93 years </td> <td> </td> </tr> <tr> <td> Sex – male </td> <td> N (%) </td> <td> 34 (44%) </td> <td> 77 </td> </tr> <tr> <td> Duration of admission </td> <td> mean days (SD) </td> <td> 38.6 (47.8) </td> <td> 77 </td> </tr> <tr> <td> </td> <td> median (interquartile range) </td> <td> 24 (15–41) </td> <td> </td> </tr> <tr> <td> </td> <td> range </td> <td> 1–292 </td> <td> </td> </tr> <tr> <td> Duration of Delirium </td> <td> mean days (SD) </td> <td> 6.3 (6.1) </td> <td> 77 </td> </tr> <tr> <td> </td> <td> median (interquartile range) </td> <td> 5 (2–7) </td> <td> </td> </tr> <tr> <td> </td> <td> range </td> <td> 1–35 </td> <td> </td> </tr> <tr> <td> Medications or alcohol as cause of delirium </td> <td> N (%) </td> <td> 30 (39%) </td> <td> 76 </td> </tr> <tr> <td> Cause of delirium </td> <td> N (%) </td> <td> </td> <td> 76 </td> </tr> <tr> <td> Medications, alcohol </td> <td> </td> <td> 30 (39%) </td> <td> </td> </tr> <tr> <td> Infection </td> <td> </td> <td> 8 (11%) </td> <td> </td> </tr> <tr> <td> Cardiac </td> <td> </td> <td> 12 (16%) </td> <td> </td> </tr> <tr> <td> Metabolic </td> <td> </td> <td> 2 (3%) </td> <td> </td> </tr> <tr> <td> Other </td> <td> </td> <td> 24 (32%) </td> <td> </td> </tr> <tr> <td> Agitation present </td> <td> N (%) </td> <td> 12 (18%) </td> <td> 65 </td> </tr> <tr> <td> Poor recognition of delirium </td> <td> N (%) </td> <td> 25 (32%) </td> <td> 77 </td> </tr> <tr> <td> GSS – Frailty </td> <td> N (%) </td> <td> </td> <td> 77 </td> </tr> <tr> <td> 1 – healthy, independent </td> <td> </td> <td> 4 (5%) </td> <td> </td> </tr> <tr> <td> 2 – mild impairment </td> <td> </td> <td> 10 (13%) </td> <td> </td> </tr> <tr> <td> 3 – moderate impair. </td> <td> </td> <td> 26 (34%) </td> <td> </td> </tr> <tr> <td> 4 – moderate-severe </td> <td> </td> <td> 25 (33%) </td> <td> </td> </tr> <tr> <td> 5 – severe impairment </td> <td> </td> <td> 10 (13%) </td> <td> </td> </tr> <tr> <td> 6 – totally dependent </td> <td> </td> <td> 2 (3%) </td> <td> </td> </tr> <tr> <td> 7 – terminally ill </td> <td> </td> <td> 0 </td> <td> </td> </tr> <tr> <td> Dementia </td> <td> </td> <td> </td> <td> 77 </td> </tr> <tr> <td> None </td> <td> </td> <td> 44 (57%) </td> <td> </td> </tr> <tr> <td> Mild dementia </td> <td> </td> <td> 14 (18%) </td> <td> </td> </tr> <tr> <td> Moderate dementia </td> <td> </td> <td> 15 (19%) </td> <td> </td> </tr> <tr> <td> Severe dementia </td> <td> </td> <td> 4 (5%) </td> <td> </td> </tr> <tr> <td> MMSE score/30 (SD) (on initial assessment) </td> <td> range 0–27 </td> <td> 12.5 (7.4) </td> <td> 75 </td> </tr> <tr> <td> Barthel Index score (SD) </td> <td> range </td> <td> </td> <td> </td> </tr> <tr> <td> Pre-morbid </td> <td> 42–100 </td> <td> 86.6 (17.4) </td> <td> 77 </td> </tr> <tr> <td> At hospital discharge </td> <td> 0–100 </td> <td> 78.9 (24.9) </td> <td> 71 </td> </tr> <tr> <td> At 6 month follow-up </td> <td> 6–100 </td> <td> 78.2 (22.3) </td> <td> 50 </td> </tr> <tr> <td> Mean change in Barthel Index (SD) </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> Pre-morbid to discharge </td> <td> </td> <td> -8.9 (19.7) </td> <td> 71 </td> </tr> <tr> <td> Pre-morbid to 6 month </td> <td> </td> <td> -12.7 (16.9) </td> <td> 50 </td> </tr> <tr> <td> Functional decline </td> <td> N (%) </td> <td> </td> <td> </td> </tr> <tr> <td> At hospital discharge </td> <td> </td> <td> 26 (37%) </td> <td> 70 </td> </tr> <tr> <td> At 6 months </td> <td> </td> <td> 27 (54%) </td> <td> 50 </td> </tr> </tbody> </table> </body> </html>
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Folic acid for primary prevention of neural tube defects </td> </tr> <tr> <td> </td> <td> 2. Smoking cessation and nicotine replacement </td> </tr> <tr> <td> </td> <td> 3. Treatment for Hypertension </td> </tr> <tr> <td> </td> <td> 4. Mammography and exam in women over 50 </td> </tr> <tr> <td> </td> <td> 5. STD screening for high risk groups </td> </tr> <tr> <td> </td> <td> 6. Papanicolaou smears for sexually active women </td> </tr> <tr> <td> </td> <td> 7. Influenza vaccination to patients 65 and older </td> </tr> <tr> <td> </td> <td> 8. Blood pressure measurement for patients 21 to 64 years of age </td> </tr> <tr> <td> <b> D <sup> ψ </sup> - category: </b> (Inappropriate) </td> <td> 1. Proteinuria screening for general population </td> </tr> <tr> <td> </td> <td> 2. Blood glucose for the general population </td> </tr> <tr> <td> </td> <td> 3. Prostate-specific antigen testing for men over 50 </td> </tr> <tr> <td> </td> <td> 4. Chest radiography </td> </tr> <tr> <td> </td> <td> 5. 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</td> </tr> <tr> <td> Incidence of breast cancer </td> <td> .001616 </td> <td> (42) </td> </tr> <tr> <td> Specificity of mammogram </td> <td> 96.5% </td> <td> (3) </td> </tr> <tr> <td> Cost of Biopsy </td> <td> $2,164 </td> <td> (42) </td> </tr> <tr> <td> Chest X-Ray </td> <td> </td> <td> </td> </tr> <tr> <td> Difference in eligible patients not screened </td> <td> 276 (-271, 822) </td> <td> (36) </td> </tr> <tr> <td> Cost of chest x-ray </td> <td> $233 </td> <td> (40) </td> </tr> <tr> <td> Urine Proteinuria Screening </td> <td> </td> <td> </td> </tr> <tr> <td> Difference in eligible patients not screened </td> <td> 9947 (7934,11961) </td> <td> (36) </td> </tr> <tr> <td> Specificity of urine dipstick test </td> <td> 95% </td> <td> (3) </td> </tr> <tr> <td> Cost of Urine culture and urinalysis </td> <td> $27.18 </td> <td> (57) </td> </tr> </tbody> </table> </body> </html>
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font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Registration </b> </td> <td colspan="2"> <b> Priority 1 </b> </td> <td colspan="2"> <b> Priority 2 </b> </td> <td colspan="2"> <b> Priority 3 </b> </td> </tr> </thead> <tbody> <tr> <td> <b> period </b> </td> <td> <b> N </b> </td> <td> <b> (%) </b> </td> <td> <b> N </b> </td> <td> <b> (%) </b> </td> <td> <b> N </b> </td> <td> <b> (%) </b> </td> </tr> <tr> <td> 1991–1992 </td> <td> 116 </td> <td> (6.7) </td> <td> 1221 </td> <td> (70.8) </td> <td> 334 </td> <td> (19.4) </td> </tr> <tr> <td> 1993–1994 </td> <td> 110 </td> <td> (5.8) </td> <td> 1381 </td> <td> (73.1) </td> <td> 388 </td> <td> (20.5) </td> </tr> <tr> <td> 1995–1996 </td> <td> 249 </td> <td> (12.4) </td> <td> 1363 </td> <td> (67.8) </td> <td> 374 </td> <td> (18.6) </td> </tr> <tr> <td> 1997–1998 </td> <td> 117 </td> <td> (6.2) </td> <td> 1327 </td> <td> (70.3) </td> <td> 428 </td> <td> (22.7) </td> </tr> <tr> <td> 1999–2000 </td> <td> 67 </td> <td> (3.9) </td> <td> 1204 </td> <td> (70.0) </td> <td> 439 </td> <td> (25.5) </td> </tr> </tbody> </table> </body> </html>
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font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Registration period </b> </td> <td> <b> Number of operations </b> </td> <td> <b> Total wait time, weeks </b> </td> <td> <b> Crude Rate, per 100 </b> </td> <td> <b> SE </b> </td> <td> <b> Hazard ratio </b> </td> <td> <b> 95% CI* </b> </td> </tr> </thead> <tbody> <tr> <td> 1991–1992 </td> <td> 1504 </td> <td> 23047 </td> <td> 6.5 </td> <td> 0.2 </td> <td> 1.00 </td> <td> referent </td> </tr> <tr> <td> 1993–1994 </td> <td> 1646 </td> <td> 25480 </td> <td> 6.5 </td> <td> 0.2 </td> <td> 1.00 </td> <td> 0.93, 1.08 </td> </tr> <tr> <td> 1995–1996 </td> <td> 1727 </td> <td> 34186 </td> <td> 5.1 </td> <td> 0.1 </td> <td> 0.70 </td> <td> 0.65, 0.76 </td> </tr> <tr> <td> 1997–1998 </td> <td> 1613 </td> <td> 30384 </td> <td> 5.3 </td> <td> 0.1 </td> <td> 0.77 </td> <td> 0.71, 0.83 </td> </tr> <tr> <td> 1999–2000 </td> <td> 1501 </td> <td> 24029 </td> <td> 6.2 </td> <td> 0.2 </td> <td> 0.94 </td> <td> 0.88, 1.02 </td> </tr> <tr> <td> All periods </td> <td> 7991 </td> <td> 137126 </td> <td> 5.8 </td> <td> 0.1 </td> <td> - </td> <td> - </td> </tr> </tbody> </table> </body> </html>
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<td> <b> Specialist visits </b> </td> <td> <b> GP visits </b> </td> <td> <b> Total </b> </td> <td> <b> % </b> </td> </tr> </thead> <tbody> <tr> <td> <b> factors influencing health status and contact with health services (V01–V83) </b> </td> <td> rehabilitation (4) </td> <td> = </td> <td> rehabilitation (5); problems of eye (7), heart (3), diabetes (2), urogenital (2), skin (1); Rx of hip (1) </td> <td> general control (8); urinary cathether substitution (1) </td> <td> 34 </td> <td> 19.3 </td> </tr> <tr> <td> <b> symptoms, signs, and ill-defined conditions (780–799) </b> </td> <td> chest pain (2); sleep disturbance (1); epistaxis (1); abdominal pain (1) </td> <td> abdominal pain (2); dyskinesia (1); epistaxis (1); dysphagia (1) </td> <td> abdominal pain (6); hallucination (1); headache (1) </td> <td> abdominal pain (2); hallucination (1); cough (1); nausea, vomiting (1); urinary incontinence (1) </td> <td> 24 </td> <td> 13.7 </td> </tr> <tr> <td> <b> injury (800–959) </b> </td> <td> fracture of femur (1), femur plus humerus (1) </td> <td> injuries due to falls (11); fractures: ribs (2), wrist (1), upper limb (1), foot (1), unspecified (2); open wound (1) </td> <td> = </td> <td> fracture unspecified (1); open wound (1) </td> <td> 23 </td> <td> 13.1 </td> </tr> <tr> <td> <b> diseases of musculo-skeletal system and connective tissue (710–739) </b> </td> <td> osteoarthrosis (1) </td> <td> pain in joint (1); lumbago (1) </td> <td> intervertebral discopathy (3); lumbago (3); pain in joint (2); osteoarthrosis (2); spondilosis (1); osteomyelitis (1) </td> <td> pain in joint (4); lumbago (2); rheumatism (1) </td> <td> 22 </td> <td> 12.5 </td> </tr> <tr> <td> <b> diseases of the circulatory system (390–459) </b> </td> <td> acute hypotension (2); cerebral ischemia (1); aortic aneurysm (1) </td> <td> = </td> <td> hypertension (3); ischemic heart disease (2); atrial fibrillation (1); myocardial degeneration (1); aortic aneurysm (1); varicous veins (1) </td> <td> hypotension (2); hypertenson (1) </td> <td> 16 </td> <td> 9.1 </td> </tr> <tr> <td> <b> diseases of the nervous system and sense organs (320–389) </b> </td> <td> cataract (3) </td> <td> hearing loss (1) </td> <td> tinnitus (1); presbyopia (1); cataract (1); hearing loss (2); glaucoma (1); impacted cerumen (1) </td> <td> conjunctivitis (2); vertiginous syndrome (1) </td> <td> 14 </td> <td> 7.9 </td> </tr> <tr> <td> <b> diseases of the digestive system (520–527) </b> </td> <td> abdominal hernia (2); gastric ulcer (1); constipation (1); cholelithiasis (1) </td> <td> pulp disease (1); teeth extraction (1) </td> <td> avulsions of teeth (2); periodontal disease (1) </td> <td> constipation (2); intestinal obstruction (1); cholelithiasis (1) </td> <td> 14 </td> <td> 7.9 </td> </tr> <tr> <td> <b> diseases of respiratory system (460–519) </b> </td> <td> pneumonia (1) </td> <td> pneumonia (1) </td> <td> asthma (1) </td> <td> influenza (5); acute laringytis (1) </td> <td> 9 </td> <td> 5.1 </td> </tr> <tr> <td> <b> other* </b> </td> <td> 4 </td> <td> 1 </td> <td> 13 </td> <td> 2 </td> <td> 20 </td> <td> 11.4 </td> </tr> <tr> <td> <b> Total </b> </td> <td> 29 </td> <td> 31 </td> <td> 74 </td> <td> 42 </td> <td> 176 </td> <td> 100.0 </td> </tr> </tbody> </table> </body> </html>
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<head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> ATC (first level) </b> </td> <td> <b> ER admissions </b> </td> <td> <b> Specialist visits </b> </td> <td> <b> GP visits </b> </td> </tr> </thead> <tbody> <tr> <td> A – alimentary tract and metabolism </td> <td> 2 (2) </td> <td> 3 (2) </td> <td> 9 (7) </td> </tr> <tr> <td> B – blood and blood forming organs </td> <td> 5 (5) </td> <td> 2 (2) </td> <td> = </td> </tr> <tr> <td> C – cardiovascular system </td> <td> 6 (6) </td> <td> = </td> <td> 5 (5) </td> </tr> <tr> <td> D – dermatologicals </td> <td> 2 (2) </td> <td> = </td> <td> 1 (1) </td> </tr> <tr> <td> G – genitourinary system and sex hormones </td> <td> 4 (3) </td> <td> = </td> <td> 1 (1) </td> </tr> <tr> <td> H – systemic hormonal preparations, excluding sex hormones </td> <td> 2 (2) </td> <td> = </td> <td> = </td> </tr> <tr> <td> J – general antiinfectives for systemic use </td> <td> 6 (5) </td> <td> 4 (4) </td> <td> 7 (6) </td> </tr> <tr> <td> L – antineoplastic and immunomodulating agents </td> <td> = </td> <td> 3 (3) </td> <td> = </td> </tr> <tr> <td> M – musculo-skeletal system </td> <td> 6 (5) </td> <td> 5 (4) </td> <td> 7 (5) </td> </tr> <tr> <td> N – nervous system </td> <td> = </td> <td> 1 (1) </td> <td> 5 (5) </td> </tr> <tr> <td> P – antiparasitic products, insecticides and repellents </td> <td> = </td> <td> = </td> <td> = </td> </tr> <tr> <td> R – respiratory system </td> <td> 2 (1) </td> <td> = </td> <td> 5 (4) </td> </tr> <tr> <td> S – sensory organs </td> <td> 2 (2) </td> <td> = </td> <td> 2 (1) </td> </tr> <tr> <td> V – various </td> <td> 1 (1) </td> <td> 1 (1) </td> <td> = </td> </tr> <tr> <td> Other </td> <td> 4 (4) </td> <td> = </td> <td> 1 (1) </td> </tr> <tr> <td> Total </td> <td> 41 (37) </td> <td> 15 (13) </td> <td> 43 (36) </td> </tr> </tbody> </table> </body> </html>
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</td> <td> 0.697 </td> <td> 4.755 </td> <td> <0.001 </td> </tr> <tr> <td> Out-of-hours care is an essential part of primary care </td> <td> -0.182 </td> <td> 0.098 </td> <td> -0.273 </td> <td> -1.851 </td> <td> 0.071 </td> </tr> <tr> <td colspan="6"> <b> Integrated GP cooperative (R <sup> 2 </sup> = 0.28) n = 50 </b> </td> </tr> <tr> <td> Constant </td> <td> 101.692 </td> <td> 23.204 </td> <td> </td> <td> 4.383 </td> <td> <0.001 </td> </tr> <tr> <td> Age </td> <td> 0.073 </td> <td> 0.398 </td> <td> 0.023 </td> <td> 0.182 </td> <td> 0.856 </td> </tr> <tr> <td> Gender <sup> a </sup> </td> <td> -9.375 </td> <td> 7.335 </td> <td> -0.156 </td> <td> -1.278 </td> <td> 0.208 </td> </tr> <tr> <td> Experienced workload </td> <td> -0.648 </td> <td> 0.144 </td> <td> -0.551 </td> <td> -4.496 </td> <td> <0.001 </td> </tr> </tbody> </table> </body> </html>
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'</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td', ' colspan="2"', '>', '</td>', '</tr>', '</tbody>']}}	<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Genotype </b> </td> <td> <b> Affected subjects (n = 76) </b> </td> <td> <b> Ethnic affiliation </b> </td> </tr> </thead> <tbody> <tr> <td colspan="3"> Mutations </td> </tr> <tr> <td> 35delG / 35delG </td> <td> 7 (4 independent families) </td> <td> Russians </td> </tr> <tr> <td> 235delC / 235delC </td> <td> 1 </td> <td> Altaian </td> </tr> <tr> <td> 312del14 / 312del14 </td> <td> 1 </td> <td> Russian/Tatar </td> </tr> <tr> <td> 35delG / 235delC </td> <td> 2 (unrelated) </td> <td> 1 – Russian/Altaian, 1 – Russian </td> </tr> <tr> <td> 35delG / 312del14 </td> <td> 1 </td> <td> Russian </td> </tr> <tr> <td> R75Q <sup> a </sup> / 235delC </td> <td> 1 </td> <td> Altaian/Russian </td> </tr> <tr> <td> R75Q / 312del14 </td> <td> 2 (two sibs) </td> <td> mixed ethnicity </td> </tr> <tr> <td> R75Q/ + </td> <td> 2 (father and daughter) </td> <td> Russians </td> </tr> <tr> <td> 235delC / W172C </td> <td> 1 </td> <td> Altaian </td> </tr> <tr> <td> Total </td> <td colspan="2"> 18 (23.7%) </td> </tr> <tr> <td colspan="3"> Non-pathogenic variants </td> </tr> <tr> <td> V27I / + </td> <td> 14 (11 independent families) </td> <td> 13 Altaians, 1 Kazakh </td> </tr> <tr> <td> (V27I; E114G) <sup> b </sup> </td> <td> 7 (unrelated) </td> <td> 6 Altaians, 1 Altaian/Russian <sup> c </sup> </td> </tr> <tr> <td> IVS1+27G>C / [V27I; E114G] </td> <td> 1 </td> <td> Altaian </td> </tr> <tr> <td> Total </td> <td colspan="2"> 22 (28.9%) </td> </tr> </tbody> </table> </body> </html>
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<td> 0.048 </td> <td> 0.976 </td> <td> 159(.78) </td> <td> 45(.22) </td> <td> 0.037 </td> <td> 0.847 </td> </tr> <tr> <td> </td> <td> P(94) </td> <td> 52(.55) </td> <td> 41(.44) </td> <td> 1(.01) </td> <td> </td> <td> </td> <td> 145(.77) </td> <td> 43(.23) </td> <td> </td> <td> </td> </tr> <tr> <td> T3804A </td> <td> N(101) </td> <td> 56(.55) </td> <td> 38(.38) </td> <td> 7(.07) </td> <td> 2.17 </td> <td> 0.304 </td> <td> 152(.74) </td> <td> 52(.26) </td> <td> 0.015 </td> <td> 0.946 </td> </tr> <tr> <td> </td> <td> P(96) </td> <td> 49(.51) </td> <td> 44(.46) </td> <td> 3(.03) </td> <td> </td> <td> </td> <td> 142(.74) </td> <td> 50(.26) </td> <td> </td> <td> </td> </tr> <tr> <td> G7465A </td> <td> N(100) </td> <td> 31(.31) </td> <td> 43(.43) </td> <td> 26(.26) </td> <td> 0.46 </td> <td> 0.793 </td> <td> 105(.53) </td> <td> 95(.48) </td> <td> 0.439 </td> <td> 0.508 </td> </tr> <tr> <td> </td> <td> P(74) </td> <td> 25(.34) </td> <td> 33(.45) </td> <td> 16(.22) </td> <td> </td> <td> </td> <td> 83(.56) </td> <td> 65(.44) </td> <td> </td> <td> </td> </tr> <tr> <td> A12517C </td> <td> N(101) </td> <td> 58(.57) </td> <td> 39(.39) </td> <td> 4(.04) </td> <td> 0.232 </td> <td> 0.890 </td> <td> 155(.77) </td> <td> 47(.23) </td> <td> 0.207 </td> <td> 0.649 </td> </tr> <tr> <td> </td> <td> P(96) </td> <td> 58(.60) </td> <td> 35(.37) </td> <td> 3(.03) </td> <td> </td> <td> </td> <td> 151(.79) </td> <td> 41(.21) </td> <td> </td> <td> </td> </tr> <tr> <td> C18626G </td> <td> N(100) </td> <td> 28(.28) </td> <td> 47(.47) </td> <td> 25(.25) </td> <td> 1.24 </td> <td> 0.538 </td> <td> 103(.52) </td> <td> 97(.49) </td> <td> 0.392 </td> <td> 0.531 </td> </tr> <tr> <td> </td> <td> P(71) </td> <td> 25(.35) </td> <td> 28(.39) </td> <td> 18(.25) </td> <td> </td> <td> </td> <td> 78(.55) </td> <td> 64(.45) </td> <td> </td> <td> </td> </tr> <tr> <td> A20004C </td> <td> N(102) </td> <td> 40(.39) </td> <td> 45(.44) </td> <td> 17(.17) </td> <td> 1.726 </td> <td> 0.422 </td> <td> 125(.61) </td> <td> 79(.39) </td> <td> 1.795 </td> <td> 0.18 </td> </tr> <tr> <td> </td> <td> P(89) </td> <td> 29(.32) </td> <td> 39(.44) </td> <td> 21(.24) </td> <td> </td> <td> </td> <td> 97(.54) </td> <td> 81(.46) </td> <td> </td> <td> </td> </tr> <tr> <td> C27224T </td> <td> N(95) </td> <td> 31(.33) </td> <td> 49(.52) </td> <td> 15(.16) </td> <td> 3.58 </td> <td> 0.167 </td> <td> 111(.58) </td> <td> 79(.42) </td> <td> 2.13 </td> <td> 0.144 </td> </tr> <tr> <td> </td> <td> P(80) </td> <td> 23(.29) </td> <td> 35(.44) </td> <td> 22(.28) </td> <td> </td> <td> </td> <td> 81(.51) </td> <td> 79(.49) </td> <td> </td> <td> </td> </tr> <tr> <td> A27237G </td> <td> N(95) </td> <td> 49(.52) </td> <td> 40(.42) </td> <td> 6(.06) </td> <td> 0.57 </td> <td> 0.751 </td> <td> 138(.73) </td> <td> 52(.27) </td> <td> 0.677 </td> <td> 0.411 </td> </tr> <tr> <td> </td> <td> P(78) </td> <td> 37(.47) </td> <td> 34(.44) </td> <td> 7(.09) </td> <td> </td> <td> </td> <td> 107(.69) </td> <td> 49(.34) </td> <td> </td> <td> 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'<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '</tbody>']}}	<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Haplotype <sup> a </sup> </b> </td> <td> <b> Patient </b> </td> <td> <b> Normal </b> </td> <td> <b> Fisher's Exact Test ( <i> P </i> value) <sup> b </sup> </b> </td> <td> <b> OR <sup> b,c,d </sup> </b> </td> <td> <b> 95% CI <sup> d </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> <b> TAGTAAGACA </b> </td> <td> 0.340 </td> <td> 0.359 </td> <td> 0.755 </td> <td> 0.919 </td> <td> 0.61–1.38 </td> </tr> <tr> <td> <b> TAGAGACCTG </b> </td> <td> 0.145 </td> <td> 0.140 </td> <td> 1.000 </td> <td> 1.035 </td> <td> 0.59–1.80 </td> </tr> <tr> <td> <b> GGTTGCCCTA </b> </td> <td> 0.095 </td> <td> 0.068 </td> <td> 0.366 </td> <td> 1.439 </td> <td> 0.70–2.96 </td> </tr> <tr> <td> <b> TAGTAACACA </b> </td> <td> 0.010 </td> <td> 0.039 </td> <td> 0.105 </td> <td> 0.250 </td> <td> 0.05–1.19 </td> </tr> <tr> <td> <b> TAGTAAGATA </b> </td> <td> 0.025 </td> <td> 0.010 </td> <td> 0.278 </td> <td> 2.615 </td> <td> 0.50–13.64 </td> </tr> <tr> <td> <b> TAGTGCGACA </b> </td> <td> 0.025 </td> <td> 0.015 </td> <td> 0.498 </td> <td> 1.735 </td> <td> 0.41–7.36 </td> </tr> <tr> <td> <b> GGGAGACCCA </b> </td> <td> 0.025 </td> <td> 0 </td> <td> 0.028 </td> <td> -- </td> <td> -- </td> </tr> <tr> <td> <b> TAGTAACCTG </b> </td> <td> 0.020 </td> <td> 0 </td> <td> 0.058 </td> <td> -- </td> <td> -- </td> </tr> <tr> <td> <b> TAGTGACCTG </b> </td> <td> 0.020 </td> <td> 0.010 </td> <td> 0.443 </td> <td> 2.081 </td> <td> 0.38–11.49 </td> </tr> <tr> <td> <b> TAGAGACATG </b> </td> <td> 0.020 </td> <td> 0.019 </td> <td> 1.000 </td> <td> 1.031 </td> <td> 0.25–4.18 </td> </tr> <tr> <td> <b> GGTTGCCCTG </b> </td> <td> 0.020 </td> <td> 0.010 </td> <td> 0.443 </td> <td> 2.082 </td> <td> 0.38–11.49 </td> </tr> <tr> <td> <b> GGTAGACCCA </b> </td> <td> 0.015 </td> <td> 0.024 </td> <td> 0.724 </td> <td> 0.612 </td> <td> 0.14–2.59 </td> </tr> <tr> <td> <b> Others </b> </td> <td> 0.240 </td> <td> 0.306 </td> <td> 0.149 </td> <td> 0.717 </td> <td> 0.46–1.11 </td> </tr> <tr> <td> Total </td> <td> </td> <td> </td> <td> 0.082 </td> <td> </td> <td> </td> </tr> <tr> <td> <b> <i> P </i> value of permutation test </b> </td> <td> <b> 0.602 </b> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> </tbody> </table> </body> </html>
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TAGTGACATG </b> </td> <td> 0.185 </td> <td> 0.169 </td> <td> 0.699 </td> <td> 1.109 </td> <td> 0.66–1.85 </td> </tr> <tr> <td> <b> GGC </b> </td> <td> <b> GGTTGCCCTA </b> <b> GGGAGACCCA </b> <b> GGTTGCCCTG </b> <b> GGTAGACCCA </b> </td> <td> 0.155 </td> <td> 0.102 </td> <td> 0.137 </td> <td> 1.616 </td> <td> 0.89–2.92 </td> </tr> <tr> <td> <b> TAC </b> </td> <td> <b> TAGTAACACA </b> <b> TAGTAACCTG </b> </td> <td> 0.030 </td> <td> 0.039 </td> <td> 0.787 </td> <td> 0.765 </td> <td> 0.26–2.25 </td> </tr> <tr> <td> <b> TGG </b> </td> <td> <b> TAGCGCGACA </b> </td> <td> 0.025 </td> <td> 0.015 </td> <td> 0.498 </td> <td> 1.735 </td> <td> 0.41–7.36 </td> </tr> <tr> <td> <b> Others </b> </td> <td> </td> <td> 0.240 </td> <td> 0.306 </td> <td> 0.149 </td> <td> 0.717 </td> <td> 0.46–1.11 </td> </tr> <tr> <td> <b> Total </b> </td> <td> </td> <td> </td> <td> </td> <td> 0.446 </td> <td> </td> <td> </td> </tr> </tbody> </table> </body> </html>
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</td> <td> 72.4 </td> </tr> <tr> <td> <b> Our most sensitive search </b> di.fs.OR predict:.tw.OR specificity.tw. </td> <td> 100.0 </td> <td> 70.4 </td> <td> 1.2 </td> <td> 70.5 </td> </tr> <tr> <td> <b> Difference (our strategy – Bachmann) 95% CI for the difference </b> </td> <td> 3.1 -0.8 to 8.7† </td> <td> -1.9 -2.7 to -1.2‡ </td> <td> 0 </td> <td> -1.9 -2.7 to -1.2‡ </td> </tr> <tr> <td> <b> Bachmann's most specific search </b> sensitiv:.tw.OR detect:.tw. </td> <td> 73.7 </td> <td> Not reported </td> <td> </td> <td> Not reported </td> </tr> <tr> <td> <b> Bachmann's strategy tested in our database </b> </td> <td> 79.4 </td> <td> 90.9 </td> <td> 3.0 </td> <td> 90.8 </td> </tr> <tr> <td> <b> Our most specific search </b> specificity.tw. </td> <td> 62.9 </td> <td> 98.2 </td> <td> 11.0 </td> <td> 98.1 </td> </tr> <tr> <td> <b> Difference (our strategy – Bachmann) 95% CI for the difference </b> </td> <td> -16.5 -28.9 to -3.8‡ </td> <td> 7.3 7.0 to 7.7‡ </td> <td> 8.0 5.6 to 11.0‡ </td> 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<td> CGCTGGCATAGCTCCCCAGAGTGAAGCCTTCCCTG </td> </tr> <tr> <td> 693 </td> <td> GATCTCGGAGTCAGCTCAGTCTCTAGGAGACTG </td> </tr> <tr> <td> 699 </td> <td> GTTCGGTCTCAGGTTTAACCTGAGATTGAG </td> </tr> <tr> <td> 701 </td> <td> GTTCGGTCTCAGGTTCCCCCTGAGATTGAG </td> </tr> <tr> <td> 703 </td> <td> GACAATGGGTAGAATATTTCAACTGTTGATGC </td> </tr> <tr> <td> 708 </td> <td> GTTCGGTCTCAATTTTAAACTGAGATTGAG </td> </tr> <tr> <td> 714 </td> <td> GTTCGGTCTCAATTTTAACCTGAGATTGAG </td> </tr> <tr> <td> 722 </td> <td> GTCAGCTTTGTTTCTAGGAGACTGAGCGTTCGG </td> </tr> <tr> <td> 724 </td> <td> CTTTGTCTCTAATTTTAAACTGAGATTGAG </td> </tr> <tr> <td> 742 </td> <td> CAGCTTTGTCTCTAGCTCACTGAGCGTTCGGTC </td> </tr> <tr> <td> 744 </td> <td> CAGCTTTGTCTCTAGACTGAGCGTTCGGTC </td> </tr> <tr> <td> 750 </td> <td> CGGCAATAAGGGTGGCAAAGAGGGTCGAGC </td> </tr> <tr> <td> 801 </td> <td> CCCATGCATGATCGCGATGAACGCGAAATGAAAC </td> </tr> <tr> <td> 897 </td> <td> CCCATGCATAACTCCTATTATTAACTATTAATTG </td> </tr> <tr> <td> 898 </td> <td> CCCATGCATGAACGCGAAATGAAACTTATCTAATCAC </td> </tr> <tr> <td> 899 </td> <td> CCCATGCATCACTTGTTATGTGATCAGCTTTTGAGTG </td> </tr> <tr> <td> 900 </td> <td> CCCATGCATCAGCTTTTGAGTGAAGTGGAAACGGG </td> </tr> <tr> <td> 925 </td> <td> TAGCTACTAGACAGAAAGCTTCCTAACAAGGAGATGCAC </td> </tr> </tbody> </table> </body> </html>
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charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Rickettsia </b> </td> <td> <b> Vector tick </b> </td> <td> <b> Geographic repartition </b> </td> <td> <b> Human disease name </b> </td> <td> <b> Fever (%) </b> </td> <td> <b> Inoculation eschar (%) </b> </td> <td> <b> Cutaneous rash (%) </b> </td> <td> <b> Fatal forms </b> </td> <td> <b> Reference </b> </td> </tr> </thead> <tbody> <tr> <td> <i> R. conorii </i> , isolates Malish, Moroccan <i> R. conorii </i> , isolate Kenyan tick typhus rickettsia </td> <td> <i> Rhipicephalus </i> sp., <i> Haemaphysalis leachii </i> </td> <td> Mediterranean area, Africa </td> <td> Mediterranean spotted fever, Kenyan tick typhus, South African tick bite fever </td> <td> 100 </td> <td> 72 </td> <td> 97 </td> <td> Yes </td> <td> [45,46] </td> </tr> <tr> <td> Indian tick typhus rickettsia </td> <td> <i> Rhipicephalus sanguineus 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<b> Reaction buffer </b> </td> <td> Tris-HCl 20 nM pH = 8.4KCl 50 mMMgCl <sub> 2 </sub> 2 mM(NH <sub> 4 </sub> ) <sub> 2 </sub> SO <sub> 4 </sub> 15 mMTaq platinum buffer </td> <td> Tris-HCl 60 nM pH = 8.3MgCl <sub> 2 </sub> 2 mM(NH <sub> 4 </sub> ) <sub> 2 </sub> SO <sub> 4 </sub> 15 mM </td> <td> Tris-HCl 20 nM pH = 8.4KCl 50 mMMgCl <sub> 2 </sub> 1.5 mMTaq platinum buffer </td> </tr> <tr> <td> <b> Primers / dNTP's </b> </td> <td> 30 pmole /reaction 400 μM </td> <td> 0.25 μg/reaction 10 μM </td> <td> 0.4 μg/reaction 200 μM </td> </tr> <tr> <td> <b> DNA concentration </b> </td> <td> 157 ng/reaction) </td> <td> 157 ng/reaction </td> <td> 157 ng/reaction </td> </tr> <tr> <td> <b> PCR reaction volume </b> </td> <td> 50 μl </td> <td> 50 μl </td> <td> 50 μl </td> </tr> <tr> <td> <b> Program </b> </td> <td> 95°c for 5 min94°c for 1 min68°c for 1 min72°c for 30 sec39 cycles72 C for 7 min </td> <td> 94°c for 1 min55°c for 2 min72°c for 3 min30 cycles72°c for 7 min </td> <td> 95°c 5 min95°c 30 sec52°c 30 sec72°c 1 min35 cycles72°c for 10 min </td> </tr> <tr> <td> <b> PCR apparatus </b> </td> <td> Biometra -T Gradient </td> <td> Biometra -T Gradient </td> <td> Biometra -T Gradient </td> </tr> </tbody> </table> </body> </html>
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</b> </td> <td> <b> TK PCR </b> </td> <td> <b> Gilad PCR </b> </td> <td> <b> Gray PCR </b> </td> <td> <b> Virus Isolation </b> </td> <td> <b> History of the koi carp </b> </td> </tr> </thead> <tbody> <tr> <td> 1 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> sick fish with clinical symptoms </td> </tr> <tr> <td> 2 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor (unknown time lap after exposure). </td> </tr> <tr> <td> 3 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor (unknown time lap after exposure) from a tank with mortality. </td> </tr> <tr> <td> 4 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor (unknown time lap after exposure) from a tank with mortality. </td> </tr> <tr> <td> 5 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor moved to 30°C, then to 24°C. no mortality in the tank. </td> </tr> <tr> <td> 6 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor moved to 30°C, then moved to 24°C. 25% mortality in the tank. </td> </tr> <tr> <td> 7 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> naïve fish that lived at 16°C. No mortality in the tank. </td> </tr> <tr> <td> 8 </td> <td> + </td> <td> + </td> <td> + </td> <td> + </td> <td> fish from tank with mortality. </td> </tr> <tr> <td> 9 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> fish from tank with mortality. </td> </tr> <tr> <td> 10 </td> <td> - </td> <td> - </td> <td> - </td> <td> Pooled </td> <td> survivor, 2 years after experimental infection </td> </tr> <tr> <td> 11 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor, 2 years after experimental infection </td> </tr> <tr> <td> 12 </td> <td> - </td> <td> - </td> <td> - </td> <td> Pooled </td> <td> survivor, 1 year after experimental infection </td> </tr> <tr> <td> 13 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor, 1 year after experimental infection </td> </tr> <tr> <td> 14 </td> <td> - </td> <td> - </td> <td> - </td> <td> Pooled </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 15 </td> <td> - </td> <td> - </td> <td> - </td> <td> </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 16 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 17 </td> <td> + </td> <td> - </td> <td> - </td> <td> </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 18 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor from tank with disease- two weeks post infection. </td> </tr> <tr> <td> KF+ </td> <td> + </td> <td> + </td> <td> + </td> <td> + </td> <td> KF-1 cell line infected with KHV- Positive control. </td> </tr> <tr> <td> KF- </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> KF-1 cell line- Negative control. </td> </tr> </tbody> </table> </body> </html>
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<td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. acidophilus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. amylovorus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. helveticus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. crispatus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. perolens </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. gasseri </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. johnsonii </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. jensenii </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. reuterii </i> </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. vaginalis </i> </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> ++ <sup> b </sup> </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. brevis </i> </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. sakei </i> </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> ++ </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. casei </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. rhamnosus </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. salivarius </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> ++ </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. ruminis </i> 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rules="groups" width="100%"> <thead> <tr> <td> <b> Enzyme name </b> </td> <td> <b> Potential Inhibitor </b> </td> <td> <b> Prior testing? </b> </td> <td> <b> Reference </b> </td> </tr> </thead> <tbody> <tr> <td> acetyl-CoA carboxylase </td> <td> pseudopeptide pyrrolidine dione antibiotics </td> <td> SA, B </td> <td> [45] </td> </tr> <tr> <td> 4-amino-4-deoxychorismate synthase </td> <td> (6s)-6-fluoroshikimate </td> <td> B </td> <td> [46] </td> </tr> <tr> <td> Adenosylmethionine decarboxylase </td> <td> CGP 40215A, AdoMao </td> <td> B </td> <td> [47,48] </td> </tr> <tr> <td> asparagine synthase (glutamine-hydrolysing) </td> <td> mucochloric and mucobromic acids, L-cysteine sulfinic acid </td> <td> B </td> <td> [49,50] </td> </tr> <tr> <td> dihydrofolate reductase </td> <td> methylpteridines </td> <td> B </td> <td> [51] </td> </tr> <tr> <td> dihydropteroate synthase </td> <td> Sulfone and sulfanilamide sulfa drugs </td> <td> B </td> <td> [52,53] </td> </tr> <tr> <td> 3-dehydroquinate synthase </td> <td> carbocyclic inhibitors </td> <td> B </td> <td> [54] </td> </tr> <tr> <td> FMN adenylyltransferase (FAD synthase) </td> <td> Riboflavin 5'-pyrophosphate </td> <td> F </td> <td> [55] </td> </tr> <tr> <td> glycerol-3-phosphate dehydrogenase (NADP) </td> <td> 5-n-alk(en)ylresorcinols </td> <td> NF </td> <td> [56] </td> </tr> <tr> <td> glutamine synthetase </td> <td> L-methionine sulfoximine, aminomethylene-bisphosphonic acid derivatives </td> <td> NF </td> <td> [57,58] </td> </tr> <tr> <td> glutamyl-tRNA reductase </td> <td> see table I in paper </td> <td> NF </td> <td> [59] </td> </tr> <tr> <td> GTP cyclohydrolase I </td> <td> Diamino-6-hydroxypyrimidine, pterins </td> <td> NF </td> <td> [60,61] </td> </tr> <tr> <td> Hydroxymethylglutaryl CoA reductase (ir) </td> <td> statins </td> <td> NF </td> <td> [62,63] </td> </tr> <tr> <td> Hydroxymethylglutaryl CoA synthase (ir) </td> <td> beta-lactone, 3-Hydroxy-3-methylglutaryldithio-coenzyme A </td> <td> NF </td> <td> [64,65] </td> </tr> <tr> <td> isopentenyl-diphosphate D-isomerase </td> <td> NE21650 </td> <td> NF </td> <td> [66] </td> </tr> <tr> <td> methionine adenosyltransferase </td> <td> adduncts 14 and 16 </td> <td> B </td> <td> [67] </td> </tr> <tr> <td> Phosphatidate phosphatase </td> <td> Propranolol </td> <td> NF </td> <td> [68] </td> </tr> <tr> <td> phosphoribosylpyrophosphate synthetase </td> <td> MRPP, ARPP </td> <td> NF </td> <td> [69] </td> </tr> <tr> <td> riboflavin synthase </td> <td> 9-D-ribitylamino-1,3,7,9-tetrahydro-2,6,8-purinetriones </td> <td> B </td> <td> [70] </td> </tr> <tr> <td> spermidine synthase </td> <td> adenosylspermidine, dicyclohexylamine </td> <td> SA, B </td> <td> [71,72] </td> </tr> <tr> <td> thiamine transport via ABC system </td> <td> azidobenzoyl derivatives of thiamin, methylene blue </td> <td> F </td> <td> [73,74] </td> </tr> <tr> <td> thioredoxin reductase </td> <td> Arsenicals, Aurothioglucose </td> <td> NF </td> <td> [75,76] </td> </tr> <tr> <td> UDP-N-acetylglucosamine 4-epimerase </td> <td> uridine analogs </td> <td> NF </td> <td> [77] </td> </tr> <tr> <td> UDP-N-acetylenolpyruvoylglucosamine reductase </td> <td> 4-thiazolidinones </td> <td> B </td> <td> [78] </td> </tr> </tbody> </table> </body> </html>
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A list of advisory board members or consultants is published on the site.• The information provided is appropriate to the audience level, well-organized and easy to use.• Information is from primary resources (i.e., textual material, abstracts, Web pages).• The primary purpose of the Web page is educational and not to sell a product or service.• The source for the contents of the Web page(s) and the entity responsible for maintaining the Web site is clear.• Information is current or an update date is included.• The site provides unique information to the topic with a minimum of redundancy and overlap between resources. </td> </tr> <tr> <td> <b> NHS Direct Online </b> </td> <td> To provide high quality health information and advice for the people of England and Wales </td> <td> No information provided. </td> </tr> </tbody> </table> </body> </html>
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font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> TOTAL NO PRESCRIPTIONS IN AREA OVER THE STUDY PERIOD </b> </td> <td> <b> NUMBER WITH ERRORS OF PRESCRIPTION WRITING </b> </td> <td> <b> NUMBER WITH DRUG ERRORS </b> </td> <td> <b> TOTAL NUMBER OF SCRIPTS WITH ERRORS </b> </td> <td> <b> % OF SCRIPTS WITH ERRORS </b> </td> </tr> </thead> <tbody> <tr> <td> OPD </td> <td> <b> 144 </b> </td> <td> <b> 64 </b> </td> <td> <b> 9 </b> </td> <td> <b> 73 </b> </td> <td> <b> 50% </b> </td> </tr> <tr> <td> A&E </td> <td> <b> 1117 </b> </td> <td> <b> 56 </b> </td> <td> <b> 4 </b> </td> <td> <b> 60 </b> </td> <td> <b> 5% </b> </td> </tr> <tr> <td> DAY </td> <td> <b> 561 </b> </td> <td> <b> 24 </b> </td> <td> <b> 2 </b> </td> <td> <b> 26 </b> </td> <td> <b> 5% </b> </td> </tr> <tr> <td> CASE </td> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> WARD </td> <td> <b> 130 </b> </td> <td> <b> 0 </b> </td> <td> <b> 0 </b> </td> <td> <b> 0 </b> </td> <td> <b> 0% </b> </td> </tr> <tr> <td> </td> <td> <b> 1952 </b> </td> <td> <b> 144 (7%) </b> </td> <td> <b> 15 (1%) </b> </td> <td> <b> 159 </b> </td> <td> <b> 8% </b> </td> </tr> </tbody> </table> </body> </html>
train	495,966	{'cells': [{'tokens': ['<b>', 'G', 'R', 'A', 'D', 'E', ' ', 'O', 'F', ' ', 'D', 'O', 'C', 'T', 'O', 'R', '</b>'], 'bbox': [4, 5, 93, 14]}, {'tokens': ['<b>', 'E', 'R', 'R', 'O', 'R', 'S', ' ', 'O', 'F', ' ', 'P', 'R', 'E', 'S', 'C', 'R', 'I', 'P', 'T', 'I', 'O', 'N', ' ', 'W', 'R', 'I', 'T', 'I', 'N', 'G', '</b>'], 'bbox': [171, 5, 330, 14]}, {'tokens': ['<b>', 'D', 'R', 'U', 'G', ' ', 'R', 'E', 'L', 'A', 'T', 'E', 'D', ' ', 'E', 'R', 'R', 'O', 'R', 'S', '</b>'], 'bbox': [337, 5, 444, 14]}, {'tokens': ['<b>', 'S', 'E', 'N', 'I', 'O', 'R', '</b>'], 'bbox': [4, 27, 39, 36]}, {'tokens': ['5', '8', ' ', '(', '4', '6', '%', ')'], 'bbox': [171, 27, 202, 36]}, {'tokens': ['0', '%'], 'bbox': [337, 27, 349, 36]}, {'tokens': ['<b>', 'J', 'U', 'N', 'I', 'O', 'R', '</b>'], 'bbox': [4, 37, 38, 46]}, {'tokens': ['6', '8', ' ', '(', '5', '4', '%', ')'], 'bbox': [171, 37, 202, 47]}, {'tokens': ['1', '5', ' ', '(', '1', '0', '0', '%', ')'], 'bbox': [337, 37, 373, 47]}], 'structure': {'tokens': ['<thead>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '</thead>', '<tbody>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '</tbody>']}}	<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> GRADE OF DOCTOR </b> </td> <td> <b> ERRORS OF PRESCRIPTION WRITING </b> </td> <td> <b> DRUG RELATED ERRORS </b> </td> </tr> </thead> <tbody> <tr> <td> <b> SENIOR </b> </td> <td> 58 (46%) </td> <td> 0% </td> </tr> <tr> <td> <b> JUNIOR </b> </td> <td> 68 (54%) </td> <td> 15 (100%) </td> </tr> </tbody> </table> </body> </html>
train	392,421	{'cells': [{'tokens': []}, {'tokens': ['<b>', 'S', 'e', 'r', '</b>'], 'bbox': [68, 5, 81, 14]}, {'tokens': ['<b>', 'A', 'r', 'g', '</b>'], 'bbox': [147, 5, 161, 14]}, {'tokens': ['<b>', 'T', 'o', 't', 'a', 'l', '</b>'], 'bbox': [212, 5, 232, 14]}, {'tokens': ['P', 'O', 'A', 'G'], 'bbox': [4, 27, 29, 36]}, {'tokens': ['2', '6', '6', ' ', '(', '9', '5', '%', ')'], 'bbox': [68, 27, 104, 36]}, {'tokens': ['1', '4', ' ', '(', '5', '%', ')'], 'bbox': [147, 27, 174, 36]}, {'tokens': ['2', '8', '0'], 'bbox': [212, 27, 226, 36]}, {'tokens': ['C', 'o', 'n', 't', 'r', 'o', 'l', 's'], 'bbox': [4, 37, 37, 47]}, {'tokens': ['1', '3', '4', ' ', '(', '9', '1', '.', '8', '%', ')'], 'bbox': [68, 37, 110, 47]}, {'tokens': ['1', '2', ' ', '(', '8', '.', '2', '%', ')'], 'bbox': [147, 37, 180, 47]}, {'tokens': ['1', '4', '6'], 'bbox': [212, 37, 226, 47]}, {'tokens': ['T', 'o', 't', 'a', 'l'], 'bbox': [4, 47, 24, 57]}, {'tokens': ['4', '0', '0'], 'bbox': [68, 47, 83, 57]}, {'tokens': ['2', '6'], 'bbox': [147, 47, 157, 57]}, {'tokens': ['4', '2', '6'], 'bbox': [212, 47, 226, 57]}], 'structure': {'tokens': ['<thead>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '</thead>', '<tbody>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '<tr>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '<td>', '</td>', '</tr>', '</tbody>']}}	<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> Ser </b> </td> <td> <b> Arg </b> </td> <td> <b> Total </b> </td> </tr> </thead> <tbody> <tr> <td> POAG </td> <td> 266 (95%) </td> <td> 14 (5%) </td> <td> 280 </td> </tr> <tr> <td> Controls </td> <td> 134 (91.8%) </td> <td> 12 (8.2%) </td> <td> 146 </td> </tr> <tr> <td> Total </td> <td> 400 </td> <td> 26 </td> <td> 426 </td> </tr> </tbody> </table> </body> </html>
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2.5 </td> </tr> <tr> <td> Intermediate </td> <td> <i> 52 </i> </td> <td> 0.2 </td> <td> 0.7 </td> <td> 3.1 </td> <td> 4.7 </td> <td> 2.8 </td> <td> 2.2 </td> </tr> <tr> <td> High-risk </td> <td> <i> 27 </i> </td> <td> 0.4 </td> <td> 0.8 </td> <td> 4.7 </td> <td> 6.4 </td> <td> 3.4 </td> <td> 2.9 </td> </tr> <tr> <td> <b> Routine <i> N = 202 </i> </b> </td> <td> </td> <td> <b> 0.4 </b> </td> <td> <b> 0.9 </b> </td> <td> <b> 2.9 </b> </td> <td> <b> 4.0 </b> </td> <td> <b> 1.6 </b> </td> <td> <b> 1.8 </b> </td> </tr> <tr> <td> Low-risk </td> <td> <i> 134 </i> </td> <td> 0.3 </td> <td> 0.7 </td> <td> 2.3 </td> <td> 3.8 </td> <td> 1.5 </td> <td> 1.6 </td> </tr> <tr> <td> Intermediate </td> <td> <i> 50 </i> </td> <td> 0.6 </td> <td> 0.9 </td> <td> 4.1 </td> <td> 3.8 </td> <td> 1.5 </td> <td> 1.8 </td> </tr> <tr> <td> High-risk </td> <td> <i> 18 </i> </td> <td> 0.9 </td> <td> 1.4 </td> <td> 4.6 </td> <td> 4.7 </td> <td> 2.2 </td> <td> 2.9 </td> </tr> </tbody> </table> </body> </html>
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Preventive </b> </td> <td colspan="2"> <b> Restorative </b> </td> </tr> <tr> <td> <b> Risk category at 2 yrs </b> </td> <td> <b> <i> n </i> </b> </td> <td> <b> Mean </b> </td> <td> <b> S.D. </b> </td> <td> <b> Mean </b> </td> <td> <b> S.D. </b> </td> <td> <b> Mean </b> </td> <td> <b> S.D. </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Risk-based <i> N = 245 </i> </b> </td> <td> </td> <td> <b> 177 </b> </td> <td> <b> 86 </b> </td> <td> <b> 216 </b> </td> <td> <b> 129 </b> </td> <td> <b> 111 </b> </td> <td> <b> 160 </b> </td> </tr> <tr> <td> Low-risk </td> <td> <i> 166 </i> </td> <td> 161 </td> <td> 79 </td> <td> 215 </td> <td> 132 </td> <td> 99 </td> <td> 142 </td> </tr> <tr> <td> Intermediate </td> <td> <i> 52 </i> </td> <td> 190 </td> <td> 84 </td> <td> 220 </td> <td> 114 </td> <td> 130 </td> <td> 188 </td> </tr> <tr> <td> High-risk </td> <td> <i> 27 </i> </td> <td> 251 </td> <td> 90 </td> <td> 214 </td> <td> 143 </td> <td> 149 </td> <td> 200 </td> </tr> <tr> <td> <b> Routine <i> N = 202 </i> </b> </td> <td> </td> <td> <b> 156 </b> </td> <td> <b> 56 </b> </td> <td> <b> 312 </b> </td> <td> <b> 84 </b> </td> <td> <b> 188 </b> </td> <td> <b> 244 </b> </td> </tr> <tr> <td> Low-risk </td> <td> <i> 134 </i> </td> <td> 140 </td> <td> 49 </td> <td> 305 </td> <td> 85 </td> <td> 133 </td> <td> 188 </td> </tr> <tr> <td> Intermediate </td> <td> <i> 50 </i> </td> <td> 186 </td> <td> 50 </td> <td> 319 </td> <td> 88 </td> <td> 263 </td> <td> 249 </td> </tr> <tr> <td> High-risk </td> <td> <i> 18 </i> </td> <td> 192 </td> <td> 72 </td> <td> 346 </td> <td> 59 </td> <td> 388 </td> <td> 406 </td> </tr> </tbody> </table> </body> </html>
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<td> Pneumonia in the newborn infant </td> <td> 31 </td> </tr> <tr> <td> Low birth weight </td> <td> 16 </td> </tr> <tr> <td> Jaundice in the newborn infant </td> <td> 12 </td> </tr> <tr> <td> Neonatal death </td> <td> 7 </td> </tr> <tr> <td> Breathing problem in the newborn infant </td> <td> 6 </td> </tr> <tr> <td> Infant not feeding </td> <td> 4 </td> </tr> <tr> <td> Green stool in the newborn infant </td> <td> 3 </td> </tr> <tr> <td> Wounds in the newborn infant </td> <td> 2 </td> </tr> <tr> <td> Tetanus in the newborn infant </td> <td> 1 </td> </tr> <tr> <td> Eye and ear infection in the newborn infant </td> <td> 1 </td> </tr> <tr> <td> Maternal problems </td> <td> </td> </tr> <tr> <td> Retained placenta </td> <td> 58 </td> </tr> <tr> <td> Vaginal Discharge </td> <td> 42 </td> </tr> <tr> <td> Malpresentation </td> <td> 30 </td> </tr> <tr> <td> Headache in the mother </td> <td> 22 </td> </tr> <tr> <td> Post partum haemorrhage </td> <td> 20 </td> </tr> <tr> <td> Fever (unspecified if 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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Clinical and laboratory parameters </b> </td> <td> <b> FS <sup> a </sup> = 0 </b> </td> <td> <b> 0 < FS < 1 </b> </td> <td> <b> 1 ≤ FS < 2 </b> </td> <td> <b> FS ≥ 2 </b> </td> </tr> </thead> <tbody> <tr> <td> No. of patients </td> <td> 57 </td> <td> 11 </td> <td> 15 </td> <td> 37 </td> </tr> <tr> <td> Sex </td> <td> 9M/48F </td> <td> 1 M/10 F </td> <td> 0 M/15 F </td> <td> 3 M/34 F </td> </tr> <tr> <td> Age (years) </td> <td> 46 ± 12 </td> <td> 46 ± 11 </td> <td> 54 ± 14 </td> <td> 56 ± 13 </td> </tr> <tr> <td> Baseline biopsy area (mm <sup> 2 </sup> ) </td> <td> 6.1 ± 5.6 </td> <td> 8.3 ± 2.8 </td> <td> 8.6 ± 4.3 </td> <td> 4.7 ± 2.6 </td> </tr> <tr> <td> Cumulative area of three biopsies (mm <sup> 2 </sup> ) </td> <td> 17.1 ± 15.1 </td> <td> 21.8 ± 9.3 </td> <td> 22.6 ± 12.7 </td> <td> 12.9 ± 6.4 </td> </tr> <tr> <td> Findings [No. (%)] </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> Dry eyes </td> <td> 49 (86) </td> <td> 9 (81) </td> <td> 14 (93) </td> <td> 33 (89) </td> </tr> <tr> <td> Xerostomia </td> <td> 45 (79) </td> <td> 7 (63) </td> <td> 14 (93) </td> <td> 35 (94) </td> </tr> <tr> <td> Positive Schirmer's test </td> <td> 24 (42) </td> <td> 4 (36) </td> <td> 9 (60) </td> <td> 18 (51) </td> </tr> <tr> <td> Reduced salivary flow rate </td> <td> 30 (53) </td> <td> 7 (63) </td> <td> 13 (86) </td> <td> 34 (91) </td> </tr> <tr> <td> Antinuclear antibodies </td> <td> 29 (51) </td> <td> 8 (73) </td> <td> 8 (53) </td> <td> 31 (83) </td> </tr> <tr> <td> Ro/SS-A </td> <td> 18 (31) </td> <td> 3 (27) </td> <td> 6 (40) </td> <td> 25 (67) </td> </tr> <tr> <td> La/SS-B </td> <td> 3 (5) </td> <td> 0 </td> <td> 3 (20) </td> <td> 10 (27) </td> </tr> <tr> <td> Rheumatoid factor </td> <td> 27 (47) </td> <td> 5 (45) </td> <td> 7 (46) </td> <td> 33 (89) </td> </tr> <tr> <td> SS according to AECG criteria [No. (%)] </td> <td> 7 (12) </td> <td> 1 (9) </td> <td> 15 (100) </td> <td> 34 (92) </td> </tr> <tr> <td> SS according to clinical re-evaluation [No. (%)] </td> <td> 7 (12) </td> <td> 0 (0) </td> <td> 8 (53) </td> <td> 34 (92) </td> </tr> </tbody> </table> </body> </html>

train

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train

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train

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train

280,628

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> </td> <td> </td> <td colspan="2"> <b> 100 × CD4 <sup> + </sup> CD25 <sup> + </sup> /CD4 <sup> + </sup> ( <i> N </i> ) </b> </td> </tr> <tr> <td> <b> Treatment </b> </td> <td> <b> Expt no. </b> </td> <td> <b> Organ </b> </td> <td> <b> IFN-γR KO </b> </td> <td> <b> WT </b> </td> </tr> </thead> <tbody> <tr> <td> Naive </td> <td> 1 </td> <td> Thymus </td> <td> 3.2 ± 0.6 (5) </td> <td> 2.2 ± 0.7 (5) </td> </tr> <tr> <td> </td> <td> </td> <td> Spleen </td> <td> 10.1 ± 0.9 (3) * </td> <td> 7.4 ± 0.2 (3) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 6.9 ± 1.1 (5) </td> <td> 5.1 ± 1.1 (5) </td> </tr> <tr> <td> </td> <td> 2 </td> <td> Spleen </td> <td> 14.4 (1) </td> <td> 9.9 (1) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 9.1 ± 0.9 (4) </td> <td> 6.6 ± 0.7 (4) </td> </tr> <tr> <td> </td> <td> 3 </td> <td> Lymph nodes </td> <td> 11.2 (1) </td> <td> 7.0 (1) </td> </tr> <tr> <td> CIA </td> <td> 4 </td> <td> Thymus </td> <td> 3.5 ± 0.9 (3) </td> <td> 4.0 ± 1.6 (3) </td> </tr> <tr> <td> </td> <td> </td> <td> Spleen </td> <td> 11.0 ± 1.3 (2) </td> <td> 7.9 ± 0.7 (2) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 10.2 ± 0.8 (6) </td> <td> 7.7 ± 0.6 (6) </td> </tr> <tr> <td> </td> <td> 5 </td> <td> Spleen </td> <td> 12.1 ± 2.9 (3) </td> <td> 9.2 ± 0.8 (3) </td> </tr> <tr> <td> </td> <td> </td> <td> Lymph nodes </td> <td> 12.9 ± 1.4 (4) </td> <td> 10.3 ± 1.1 (4) </td> </tr> <tr> <td> </td> <td> 6 </td> <td> Lymph nodes </td> <td> 13.4 ± 0.4 (4) * </td> <td> 9.2 ± 0.7 (4) </td> </tr> </tbody> </table> </body> </html>

train

453,722

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Feature </b> </td> <td> <b> Scoring system </b> </td> </tr> </thead> <tbody> <tr> <td> <i> Assessed by histology </i> </td> <td> </td> </tr> <tr> <td> Lining-layer hyperplasia </td> <td> Semiquantitative </td> </tr> <tr> <td> Degree of vascularity </td> <td> Semiquantitative </td> </tr> <tr> <td> Inflammatory infiltration </td> <td> Semiquantitative </td> </tr> <tr> <td> Lymphoid aggregates </td> <td> Present or absent </td> </tr> <tr> <td> Plasma cells </td> <td> Semiquantitative </td> </tr> <tr> <td> Polymorphonuclear leukocytes </td> <td> Semiquantitative </td> </tr> <tr> <td> <i> Assessed by immunohistochemistry </i> </td> <td> </td> </tr> <tr> <td> CD1a </td> <td> Present or absent </td> </tr> <tr> <td> CD3 </td> <td> Semiquantitative </td> </tr> <tr> <td> CD20 </td> <td> Semiquantitative </td> </tr> <tr> <td> CD68 lining layer </td> <td> Semiquantitative </td> </tr> <tr> <td> CD68 sublining layer </td> <td> Semiquantitative </td> </tr> <tr> <td> CD163 lining layer </td> <td> Semiquantitative </td> </tr> <tr> <td> CD163 sublining layer </td> <td> Semiquantitative </td> </tr> <tr> <td> Intracellular citrullinated peptides </td> <td> Present or absent </td> </tr> <tr> <td> MHC class II–HC gp39 peptide complex, recognized by mAb 12A </td> <td> Present or absent </td> </tr> </tbody> </table> </body> </html>

train

89,447

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Group </b> </td> <td> <b> KC </b> </td> <td> <b> MIP1α </b> </td> </tr> </thead> <tbody> <tr> <td> ICA, day 3 </td> <td> </td> <td> </td> </tr> <tr> <td> AxCANI </td> <td> 56 ± 8 </td> <td> 303 ± 6.8 </td> </tr> <tr> <td> AxCAhIL-13 </td> <td> 196 ± 31* </td> <td> 344 ± 96 </td> </tr> <tr> <td> ICA, day 7 </td> <td> </td> <td> </td> </tr> <tr> <td> AxCANI </td> <td> 10 ± 6 </td> <td> 157 ± 25 </td> </tr> <tr> <td> AxCAhIL-13 </td> <td> 184 ± 26* </td> <td> 268 ± 98 </td> </tr> </tbody> </table> </body> </html>

train

274,056

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Essential oil </b> </td> <td> <b> Parent plant </b> </td> <td> <b> Main constituents </b> </td> <td> <b> Manufacturer of the oil </b> </td> <td> <b> References for clinical use </b> </td> </tr> </thead> <tbody> <tr> <td> Eucalyptus </td> <td> <i> Eucalyptus glogulus </i> </td> <td> 1,8 – cineole </td> <td> Sanoflore (France) </td> <td> 11 </td> </tr> <tr> <td> Tea tree </td> <td> <i> Melaleuca alternifolia </i> </td> <td> terpinen-4-ol </td> <td> Sanoflore (France) </td> <td> 12,13 </td> </tr> <tr> <td> True Lavender </td> <td> <i> Lavandula angustifolia </i> </td> <td> linalool </td> <td> Sanoflore (France) </td> <td> 11–13 </td> </tr> <tr> <td> Geranium Bourbon </td> <td> <i> Perargonium asperum </i> </td> <td> geraniol, β-citronellol </td> <td> Sanoflore (France) </td> <td> 11–13 </td> </tr> <tr> <td> Juniper </td> <td> <i> Juniperus communis </i> </td> <td> α-pinene </td> <td> Sanoflore (France) </td> <td> 11–13 </td> </tr> </tbody> </table> </body> </html>

train

283,792

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train

336,534

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train

284,386

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train

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train

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Plant tested </b> </td> <td colspan="2"> <b> Water extract </b> </td> <td colspan="2"> <b> Ethanol extract </b> </td> </tr> <tr> <td> </td> <td> <b> MIC </b> </td> <td> <b> MBC </b> </td> <td> <b> MIC </b> </td> <td> <b> MBC </b> </td> </tr> </thead> <tbody> <tr> <td> <i> B. ferruginea </i> </td> <td> 55.4 </td> <td> 63.6 </td> <td> 30.6 </td> <td> 55.0 </td> </tr> <tr> <td> <i> A. conyzoides </i> </td> <td> 71.0 </td> <td> 84.2 </td> <td> 43.0 </td> <td> 63.2 </td> </tr> <tr> <td> <i> T. avicennioides </i> </td> <td> 20.8 </td> <td> 33.0 </td> <td> 18.2 </td> <td> 30.4 </td> </tr> <tr> <td> <i> P. discoideus </i> </td> <td> 23.0 </td> <td> 34.2 </td> <td> 20.5 </td> <td> 33.0 </td> </tr> <tr> <td> <i> O. gratissimum </i> </td> <td> 25.0 </td> <td> 37.0 </td> <td> 22.3 </td> <td> 35.2 </td> </tr> <tr> <td> <i> A. wilkesiana </i> </td> <td> 24.5 </td> <td> 37.0 </td> <td> 24. </td> <td> 37.0 </td> </tr> </tbody> </table> </body> </html>

train

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train

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train

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Localization </b> </td> <td> <b> Total number of catheters </b> </td> <td> <b> Duration of catheter use (days) </b> </td> <td> <b> Not colonized n (%) </b> </td> <td> <b> Colonized n (%) </b> </td> <td> <b> Colonized <i> and </i> local infectious signs; n (%) </b> </td> </tr> </thead> <tbody> <tr> <td> Epidural catheter (C6/7 - T2/3) </td> <td> 29 </td> <td> 6 (5 / 8) </td> <td> 29 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Epidural catheter (T3/4 - T 12/L1) </td> <td> 59 </td> <td> 4 (3 / 6) </td> <td> 51 (86.4%) </td> <td> 8 (13.6%) </td> <td> 4 (6.8%) </td> </tr> <tr> <td> Epidural catheter (L1/2 - L4/5) </td> <td> 8 </td> <td> 4 (3 / 6) </td> <td> 7 (87.5%) </td> <td> 1 (12.5%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Paravertebral catheter (level T3 - T8) </td> <td> 4 </td> <td> 1 (1 / 3) </td> <td> 4 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Psoas compartment </td> <td> 5 </td> <td> 4 (3 / 4) </td> <td> 4 (80%) </td> <td> 1 (20%) </td> <td> 1 (20%) </td> </tr> <tr> <td> Posterior sciatic (gluteal) </td> <td> 1 </td> <td> 2 </td> <td> 1 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Distal sciatic (popliteal) </td> <td> 1 </td> <td> 2 </td> <td> 1 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Anterior sciatic (proximal) </td> <td> 7 </td> <td> 2 (1 / 3) </td> <td> 4 (57.1%) </td> <td> 3 (42.9%) </td> <td> 1 (14.3%) </td> </tr> <tr> <td> Femoral nerve </td> <td> 68 </td> <td> 3 (1 / 3) </td> <td> 50 (73.5%) </td> <td> 18 (26.5%) </td> <td> 10 (14.7%) </td> </tr> <tr> <td> Interscalene plexus </td> <td> 9 </td> <td> 2 (1 / 3) </td> <td> 8 (88.9%) </td> <td> 1 (11.1%) </td> <td> 1 (11.1%) </td> </tr> <tr> <td> Infraclavicular plexus </td> <td> 5 </td> <td> 3 (2 / 6) </td> <td> 4 (80%) </td> <td> 1 (20%) </td> <td> 1 (20%) </td> </tr> <tr> <td> Axillary plexus </td> <td> 2 </td> <td> 3 (1 / 4) </td> <td> 2 (100%) </td> <td> 0 (0%) </td> <td> 0 (0%) </td> </tr> <tr> <td> Total </td> <td> 198 </td> <td> 3 (2 / 5) </td> <td> 151 (83.3%) </td> <td> 33 (16.7%) </td> <td> 18 (9.1%) </td> </tr> </tbody> </table> </body> </html>

train

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Case </b> </td> <td> <b> Nucleotide Substitution <sup> a </sup> </b> </td> <td> <b> Amino acid change </b> </td> <td> <b> Age </b> </td> <td> <b> Sex </b> </td> <td> <b> MSI Status <sup> b,c </sup> </b> </td> <td> <b> <i> KRAS </i> Mutation <sup> c </sup> </b> </td> <td> <b> Tumour site </b> </td> <td> <b> Tumour type </b> </td> <td> <b> IM <sup> d </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> 28 </td> <td> A3140G </td> <td> H1047R </td> <td> 37 </td> <td> M </td> <td> Stable </td> <td> - </td> <td> Body </td> <td> Intestinal </td> <td> 0 </td> </tr> <tr> <td> 100 </td> <td> G1633A </td> <td> E545K </td> <td> 79 </td> <td> F </td> <td> High </td> <td> - </td> <td> Antrum </td> <td> Intestinal </td> <td> 1 </td> </tr> <tr> <td> 240 </td> <td> G1624A </td> <td> E542K </td> <td> 74 </td> <td> M </td> <td> High </td> <td> G12D </td> <td> Antrum </td> <td> Intestinal </td> <td> 1 </td> </tr> <tr> <td> 310 </td> <td> A3140G </td> <td> H1047R </td> <td> 72 </td> <td> F </td> <td> High </td> <td> G13D </td> <td> Antrum </td> <td> Intestinal </td> <td> 1 </td> </tr> </tbody> </table> </body> </html>

train

173,470

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Median age (range), yrs </b> </td> <td> <b> 64 (60–73) </b> </td> </tr> <tr> <td> <b> Age category, n (%) </b> </td> <td> </td> </tr> <tr> <td> <b> >60 and < 65 years </b> </td> <td> <b> 100 (56) </b> </td> </tr> <tr> <td> <b> ≥ 65 years </b> </td> <td> <b> 80 (44) </b> </td> </tr> </thead> <tbody> <tr> <td> pT-category, n (%) </td> <td> </td> </tr> <tr> <td> pT1 </td> <td> 73 (41) </td> </tr> <tr> <td> pT2 </td> <td> 91 (51) </td> </tr> <tr> <td> pT3 </td> <td> 5 (3) </td> </tr> <tr> <td> pT4 </td> <td> 3 (2) </td> </tr> <tr> <td> unknown </td> <td> 8 (4) </td> </tr> <tr> <td> pN-category, n (%) </td> <td> </td> </tr> <tr> <td> pN0 </td> <td> 66 (37) </td> </tr> <tr> <td> pN1 </td> <td> 97 (54) </td> </tr> <tr> <td> pN2 </td> <td> 10 (6) </td> </tr> <tr> <td> unknown </td> <td> 7 (4) </td> </tr> <tr> <td> Receptor status, n (%) </td> <td> </td> </tr> <tr> <td> ER or PgR positive </td> <td> 82 (46) </td> </tr> <tr> <td> Negative </td> <td> 78 (43) </td> </tr> <tr> <td> Unknown </td> <td> 20 (11) </td> </tr> <tr> <td> Histotype, n (%) </td> <td> </td> </tr> <tr> <td> Ductal </td> <td> 132 (73) </td> </tr> <tr> <td> Lobular </td> <td> 33 (18) </td> </tr> <tr> <td> Other </td> <td> 15 (8) </td> </tr> <tr> <td> Histologic grade, n (%) </td> <td> </td> </tr> <tr> <td> G1 </td> <td> 5 (3) </td> </tr> <tr> <td> G2 </td> <td> 53 (29) </td> </tr> <tr> <td> G3 </td> <td> 96 (53) </td> </tr> <tr> <td> Unknown </td> <td> 26 (14) </td> </tr> <tr> <td> Concomitant radiotherapy, n (%) </td> <td> </td> </tr> <tr> <td> No </td> <td> 114 (63) </td> </tr> <tr> <td> Yes </td> <td> 66 (37) </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td colspan="3"> <b> Haematologic </b> </td> <td colspan="3"> <b> Other </b> </td> <td colspan="3"> <b> Any </b> </td> </tr> <tr> <td> <b> Subgroup </b> </td> <td> <b> G0-2 </b> </td> <td> <b> G3-4 </b> </td> <td> <b> p* </b> </td> <td> <b> G0-2 </b> </td> <td> <b> G3-4 </b> </td> <td> <b> p* </b> </td> <td> <b> G0-2 </b> </td> <td> <b> G3-4 </b> </td> <td> <b> p* </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Age </b> </td> <td> </td> <td> </td> <td> 0.17 </td> <td> </td> <td> </td> <td> 0.49 </td> <td> </td> <td> </td> <td> 1.00 </td> </tr> <tr> <td> >60 and <65 years ( <i> n = 100 </i> ) </td> <td> 86% </td> <td> 14% </td> <td> </td> <td> 72% </td> <td> 28% </td> <td> </td> <td> 62% </td> <td> 38% </td> <td> </td> </tr> <tr> <td> ≥ 65 years ( <i> n = 80 </i> ) </td> <td> 78% </td> <td> 22% </td> <td> </td> <td> 78% </td> <td> 22% </td> <td> </td> <td> 61% </td> <td> 39% </td> <td> </td> </tr> <tr> <td> <b> Radiotherapy </b> </td> <td> </td> <td> </td> <td> <0.0001 </td> <td> </td> <td> </td> <td> 0.21 </td> <td> </td> <td> </td> <td> 0.27 </td> </tr> <tr> <td> No ( <i> n = 114 </i> ) </td> <td> 92% </td> <td> 8% </td> <td> </td> <td> 71% </td> <td> 29% </td> <td> </td> <td> 65% </td> <td> 35% </td> <td> </td> </tr> <tr> <td> Yes ( <i> n = 66 </i> ) </td> <td> 65% </td> <td> 35% </td> <td> </td> <td> 80% </td> <td> 20% </td> <td> </td> <td> 56% </td> <td> 44% </td> <td> </td> </tr> <tr> <td> <b> Age and radiotherapy </b> </td> <td> </td> <td> </td> <td> <0.0001 </td> <td> </td> <td> </td> <td> 0.42 </td> <td> </td> <td> </td> <td> 0.08 </td> </tr> <tr> <td> >60 and < 65, no RT ( <i> n = 64 </i> ) </td> <td> 92% </td> <td> 8% </td> <td> </td> <td> 67% </td> <td> 33% </td> <td> </td> <td> 59% </td> <td> 41% </td> <td> </td> </tr> <tr> <td> ≥ 65, no RT ( <i> n = 50 </i> ) </td> <td> 92% </td> <td> 8% </td> <td> </td> <td> 76% </td> <td> 24% </td> <td> </td> <td> 72% </td> <td> 28% </td> <td> </td> </tr> <tr> <td> >60 and < 65, RT ( <i> n = 36 </i> ) </td> <td> 75% </td> <td> 25% </td> <td> </td> <td> 81% </td> <td> 19% </td> <td> </td> <td> 67% </td> <td> 33% </td> <td> </td> </tr> <tr> <td> ≥ 65, RT ( <i> n = 30 </i> ) </td> <td> 53% </td> <td> 47% </td> <td> </td> <td> 80% </td> <td> 20% </td> <td> </td> <td> 43% </td> <td> 57% </td> <td> </td> </tr> </tbody> </table> </body> </html>

train

329,269

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Variable </b> </td> <td colspan="3"> <b> Age </b> </td> <td colspan="3"> <b> Radiotherapy </b> </td> </tr> <tr> <td> </td> <td> <b> >60 and < 65 ( <i> n = 100 </i> ) </b> </td> <td> <b> ≥ 65 ( <i> n = 80 </i> ) </b> </td> <td> <b> P <sup> § </sup> </b> </td> <td> <b> No* ( <i> n = 114 </i> ) </b> </td> <td> <b> Yes ( <i> n = 66 </i> ) </b> </td> <td> <b> P <sup> § </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> N. of cycles administered, no. (%) </td> <td> </td> <td> </td> <td> 0.42 </td> <td> </td> <td> </td> <td> 0.01 </td> </tr> <tr> <td> 6 cycles </td> <td> 81 (81) </td> <td> 61 (76) </td> <td> </td> <td> 84 (74) </td> <td> 58 (88) </td> <td> </td> </tr> <tr> <td> 5 cycles </td> <td> 5 (5) </td> <td> 4 (5) </td> <td> </td> <td> 4 (3) </td> <td> 5 (8) </td> <td> </td> </tr> <tr> <td> 4 cycles </td> <td> 4 (4) </td> <td> 4 (5) </td> <td> </td> <td> 6 (5) </td> <td> 2 (3) </td> <td> </td> </tr> <tr> <td> 3 cycles </td> <td> 5 (5) </td> <td> 6 (8) </td> <td> </td> <td> 10 (9) </td> <td> 1 (1) </td> <td> </td> </tr> <tr> <td> 2 cycles </td> <td> 4 (4) </td> <td> 4 (5) </td> <td> </td> <td> 8 (7) </td> <td> 0 </td> <td> </td> </tr> <tr> <td> 1 cycle </td> <td> 1 (1) </td> <td> 1 (1) </td> <td> </td> <td> 2 (2) </td> <td> 0 </td> <td> </td> </tr> <tr> <td> N. of day 8 omitted, no. (%) </td> <td> </td> <td> </td> <td> 0.37 </td> <td> </td> <td> </td> <td> 0.86 </td> </tr> <tr> <td> 0 </td> <td> 69 (69) </td> <td> 51 (64) </td> <td> </td> <td> 77 (68) </td> <td> 43 (65) </td> <td> </td> </tr> <tr> <td> 1 </td> <td> 23 (23) </td> <td> 18 (22) </td> <td> </td> <td> 24 (21) </td> <td> 17 (26) </td> <td> </td> </tr> <tr> <td> 2 </td> <td> 5 (5) </td> <td> 8 (10) </td> <td> </td> <td> 9 (8) </td> <td> 4 (6) </td> <td> </td> </tr> <tr> <td> 3 </td> <td> 3 (3) </td> <td> 3 (4) </td> <td> </td> <td> 4 (3) </td> <td> 2 (3) </td> <td> </td> </tr> <tr> <td> Rate of cycles at reduced dose, no. (%) </td> <td> </td> <td> </td> <td> 0.54 </td> <td> </td> <td> </td> <td> 0.83 </td> </tr> <tr> <td> ≤ 25% </td> <td> 86 (86) </td> <td> 66 (82) </td> <td> </td> <td> 97 (85) </td> <td> 55 (83) </td> <td> </td> </tr> <tr> <td> >25% </td> <td> 14 (14) </td> <td> 14 (18) </td> <td> </td> <td> 17 (15) </td> <td> 11 (17) </td> <td> </td> </tr> <tr> <td> Actual/planned duration, no. (%) </td> <td> </td> <td> </td> <td> 0.59 </td> <td> </td> <td> </td> <td> 0.05 </td> </tr> <tr> <td> ≤ 1.25 </td> <td> 99 (99) </td> <td> 78 (98) </td> <td> </td> <td> 114 (100) </td> <td> 63 (95) </td> <td> </td> </tr> <tr> <td> >1.25 </td> <td> 1 (1) </td> <td> 2 (2) </td> <td> </td> <td> 0 </td> <td> 3 (5) </td> <td> </td> </tr> <tr> <td> G-CSF utilization, no. (%) </td> <td> </td> <td> </td> <td> 0.12 </td> <td> </td> <td> <.0001 </td> <td> </td> </tr> <tr> <td> No </td> <td> 91 (91) </td> <td> 66 (82) </td> <td> </td> <td> 109 (96) </td> <td> 48 (73) </td> <td> </td> </tr> <tr> <td> Yes </td> <td> 9 (9) </td> <td> 14 (18) </td> <td> </td> <td> 5 (4) </td> <td> 18 (27) </td> <td> </td> </tr> <tr> <td> Treatment discontinuation, no. (%) </td> <td> </td> <td> </td> <td> 0.52 </td> <td> </td> <td> </td> <td> 0.10 </td> </tr> <tr> <td> protocol completion </td> <td> 81 (81) </td> <td> 61 (76) </td> <td> </td> <td> 84 (74) </td> <td> 58 (88) </td> <td> </td> </tr> <tr> <td> patient's refusal </td> <td> 6 (6) </td> <td> 9 (11) </td> <td> </td> <td> 12 (11) </td> <td> 3 (4) </td> <td> </td> </tr> <tr> <td> treatment toxicity </td> <td> 11 (11) </td> <td> 7 (9) </td> <td> </td> <td> 13 (11) </td> <td> 5 (8) </td> <td> </td> </tr> <tr> <td> other </td> <td> 2 (2) </td> <td> 3 (4) </td> <td> </td> <td> 5 (4) </td> <td> 0 </td> <td> </td> </tr> <tr> <td> Low compliance <sup> † </sup> , no. (%) </td> <td> </td> <td> </td> <td> 0.02 </td> <td> </td> <td> </td> <td> 0.88 </td> </tr> <tr> <td> No </td> <td> 61 (61) </td> <td> 34 (42) </td> <td> </td> <td> 61 (54) </td> <td> 34 (52) </td> <td> </td> </tr> <tr> <td> yes </td> <td> 39 (39) </td> <td> 46 (58) </td> <td> </td> <td> 53 (46) </td> <td> 32 (48) </td> <td> </td> </tr> </tbody> </table> </body> </html>

train

315,783

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train

547,659

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td colspan="2"> <b> Smoking habit </b> </td> <td> <b> Acne patients (12) </b> </td> <td> <b> Control patients (27) </b> </td> </tr> </thead> <tbody> <tr> <td> Amount </td> <td> 1 cigarette per week </td> <td> 2 </td> <td> 5 </td> </tr> <tr> <td> </td> <td> 1–6 cigarettes per week </td> <td> 2 </td> <td> 9 </td> </tr> <tr> <td> </td> <td> > 6 cigarettes per week </td> <td> 8 </td> <td> 12 </td> </tr> <tr> <td> </td> <td> Not mentioned </td> <td> 0 </td> <td> 1 </td> </tr> <tr> <td> Duration </td> <td> < 3 months </td> <td> 1 </td> <td> 2 </td> </tr> <tr> <td> </td> <td> 3 months – 3 years </td> <td> 6 </td> <td> 7 </td> </tr> <tr> <td> </td> <td> > 3 years </td> <td> 5 </td> <td> 16 </td> </tr> <tr> <td> </td> <td> Not mentioned </td> <td> 0 </td> <td> 2 </td> </tr> </tbody> </table> </body> </html>

train

489,841

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Age(year) </b> </td> <td> <b> Male </b> </td> <td> <b> Female </b> </td> <td> <b> Sum </b> </td> </tr> </thead> <tbody> <tr> <td> 25–29 </td> <td> 15 </td> <td> 10 </td> <td> 25 </td> </tr> <tr> <td> 30–34 </td> <td> 48 </td> <td> 41 </td> <td> 89 </td> </tr> <tr> <td> 35–39 </td> <td> 64 </td> <td> 57 </td> <td> 121 </td> </tr> <tr> <td> 40–44 </td> <td> 95 </td> <td> 56 </td> <td> 151 </td> </tr> <tr> <td> 45–49 </td> <td> 99 </td> <td> 66 </td> <td> 165 </td> </tr> <tr> <td> 50–54 </td> <td> 25 </td> <td> 20 </td> <td> 45 </td> </tr> <tr> <td> 55–59 </td> <td> 3 </td> <td> 1 </td> <td> 4 </td> </tr> <tr> <td> Sum </td> <td> 349 </td> <td> 251 </td> <td> 600 </td> </tr> </tbody> </table> </body> </html>

train

205,413

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Dermatologic manifestation </b> </td> <td> <b> Frequency in exposure negative group </b> </td> <td> <b> Frequency in exposure positive group </b> </td> </tr> </thead> <tbody> <tr> <td> Nonspecific erythema </td> <td> 1 </td> <td> 5 </td> </tr> <tr> <td> Rosacea acnea </td> <td> 1 </td> <td> 2 </td> </tr> <tr> <td> Erythema,,Scaling </td> <td> 1 </td> <td> 3 </td> </tr> <tr> <td> Itching, Burning </td> <td> 2 </td> <td> 17 </td> </tr> <tr> <td> Sum </td> <td> 5 </td> <td> 27 </td> </tr> </tbody> </table> </body> </html>

train

546,677

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train

378,149

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Quantity </b> </td> <td> <b> Observed <i> τ </i> </b> </td> <td> <b> 95% CI </b> </td> </tr> </thead> <tbody> <tr> <td> Evolutionary Rate </td> <td> 0.24 </td> <td> 0.12–0.35 </td> </tr> <tr> <td> Connectivity </td> <td> 0.07 </td> <td> 0.001–0.14 </td> </tr> <tr> <td> Expression </td> <td> 0.32 </td> <td> 0.26–0.39 </td> </tr> </tbody> </table> </body> </html>

train

327,331

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> Number </b> </td> <td> <b> Age (years) </b> </td> <td> <b> height(cm) </b> </td> <td> <b> weight(kg) </b> </td> <td> <b> BMI </b> </td> <td> <b> HBA1C </b> </td> </tr> </thead> <tbody> <tr> <td> men </td> <td> 8 </td> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> mean </td> <td> </td> <td> 60.0 </td> <td> 185.1 </td> <td> 101.8 </td> <td> 29.6 </td> <td> 9.0 </td> </tr> <tr> <td> sd </td> <td> </td> <td> 19.9 </td> <td> 12.5 </td> <td> 24.2 </td> <td> 5.7 </td> <td> 2.8 </td> </tr> <tr> <td> women </td> <td> 8 </td> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> mean </td> <td> </td> <td> 63.8 </td> <td> 161.9 </td> <td> 83.2 </td> <td> 31.1 </td> <td> 8.4 </td> </tr> <tr> <td> sd </td> <td> </td> <td> 11.7 </td> <td> 6.3 </td> <td> 27.3 </td> <td> 7.9 </td> <td> 1.5 </td> </tr> <tr> <td> group mean </td> <td> 16 </td> <td> 61.2 </td> <td> 178.0 </td> <td> 96.1 </td> <td> 30.0 </td> <td> 8.8 </td> </tr> <tr> <td> sd </td> <td> </td> <td> 10.2 </td> <td> 15.6 </td> <td> 26.7 </td> <td> 6.3 </td> <td> 2.4 </td> </tr> </tbody> </table> </body> </html>

train

400,894

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train

294,109

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> </td> <td> <b> Behavior Problems N (%) </b> </td> <td> <b> Social-emotional difficulties N (%) </b> </td> <td> <b> ADHD N (%) </b> </td> <td> <b> Mood Disorders N (%) </b> </td> </tr> </thead> <tbody> <tr> <td> Comfort with diagnosis/ evaluation </td> <td> Low </td> <td> 147 (50.3) </td> <td> 111 (39.1) </td> <td> 136 (47.6) </td> <td> 86 (27) </td> </tr> <tr> <td> </td> <td> High </td> <td> 145 (49.7) </td> <td> 173 (60.9) </td> <td> 150 (52.4) </td> <td> 232 (73) </td> </tr> <tr> <td> Skill in diagnosis/ evaluation </td> <td> Low </td> <td> 183 (61.6) </td> <td> 152 (53) </td> <td> 144 (51.8) </td> <td> 96 (31.1) </td> </tr> <tr> <td> </td> <td> High </td> <td> 114 (38.4) </td> <td> 135 (47) </td> <td> 134 (48.2) </td> <td> 213 (68.9) </td> </tr> <tr> <td> Comfort with management </td> <td> Low </td> <td> 213 (70.5) </td> <td> 172 (59.1) </td> <td> 156 (51.1) </td> <td> 115 (35.5) </td> </tr> <tr> <td> </td> <td> High </td> <td> 89 (29.5) </td> <td> 119 (40.9) </td> <td> 149 (48.9) </td> <td> 209 (64.5) </td> </tr> <tr> <td> Effectiveness in management </td> <td> Low </td> <td> 223 (76.4) </td> <td> 192 (67.4) </td> <td> 148 (50.7) </td> <td> 104 (34.7) </td> </tr> <tr> <td> </td> <td> High </td> <td> 69 (23.6) </td> <td> 93 (32.6) </td> <td> 144 (49.3) </td> <td> 196 (65.3) </td> </tr> </tbody> </table> </body> </html>

train

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train

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> PBC (n = 45) </b> </td> <td> <b> PSC (n = 27) </b> </td> </tr> </thead> <tbody> <tr> <td> Age (mean, range in years) </td> <td> 58 (34–78) </td> <td> 45 (23–68) </td> </tr> <tr> <td> Sex (male / female) </td> <td> 4/45 </td> <td> 19/8 </td> </tr> <tr> <td> Fatigue (yes / no) </td> <td> 32/15 </td> <td> 15/12 </td> </tr> <tr> <td> Cirrhosis (yes / no) </td> <td> 12 / 33 </td> <td> 2 / 25 </td> </tr> <tr> <td> Inflammatory bowel disease (yes / no) </td> <td> 0 / 45 </td> <td> 16 / 11 </td> </tr> <tr> <td> Total serum bilirubin (median, range in μmol/l) </td> <td> 10 (4–98) </td> <td> 15 (6–37) </td> </tr> <tr> <td> Serum albumin (median, range in g/l) </td> <td> 42 (31–48) </td> <td> 42 (33–47) </td> </tr> <tr> <td> Prothrombin time (median, range in sec.) </td> <td> 12 (10–18) </td> <td> 13 (11–16) </td> </tr> <tr> <td> Serum ALT activity (median, range in U/l) </td> <td> 43 (17–484) </td> <td> 35 (10–662) </td> </tr> <tr> <td> Serum AST activity (median, range in U/l) </td> <td> 37 (21–241) </td> <td> 31 (18–338) </td> </tr> <tr> <td> Serum Alkaline Phosphatase (median, range in U/l) </td> <td> 154 (68–441) </td> <td> 147 (53–1141) </td> </tr> </tbody> </table> </body> </html>

train

462,874

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Species </b> </td> <td> <b> Accession </b> </td> <td> <b> Genome </b> </td> </tr> </thead> <tbody> <tr> <td> <i> O.sativa(Japonica) </i> </td> <td> Odaebyeo, Jinbubyeo, Jinmibyeo, Hwasungbyeo </td> <td> AA </td> </tr> <tr> <td> </td> <td> Ilpumbyeo </td> <td> </td> </tr> <tr> <td> <i> O.sativa(Indica) </i> </td> <td> China1039, IRRI57313, IRRI60820, IRRI61009 </td> <td> AA </td> </tr> <tr> <td> </td> <td> IRRI72 </td> <td> </td> </tr> <tr> <td> <i> O.rufipogon </i> </td> <td> 100647, 100657, 100678, 100692, 100898, 100916 </td> <td> AA </td> </tr> <tr> <td> </td> <td> 100926, 101173, 101193 </td> <td> </td> </tr> <tr> <td> <i> O.nivara </i> </td> <td> 100593, 100918, 104405, 105701, 100898, 100951 </td> <td> AA </td> </tr> <tr> <td> </td> <td> 100967, 103834, 103835, 103836 </td> <td> </td> </tr> <tr> <td> <i> O.glaberrima </i> </td> <td> 100982, 100983, 100984, 100980, 101297, 101303 </td> <td> AA </td> </tr> <tr> <td> </td> <td> 100140, 100149, 100152, 100854 </td> <td> </td> </tr> <tr> <td> <i> O.longistaminata </i> </td> <td> 101202, 101206, 101207, 101210, 101211, 101214 </td> <td> AA </td> </tr> <tr> <td> </td> <td> 101228, 101230, 101431 </td> <td> </td> </tr> <tr> <td> <i> O.barthii </i> </td> <td> 86447, 100117, 100122, 100223, 100224, 101257 </td> <td> AA </td> </tr> <tr> <td> </td> <td> 100933, 100936, 100941, 101226 </td> <td> </td> </tr> <tr> <td> <i> O.glumaepatula </i> </td> <td> 100969, 105662, 105670 </td> <td> AA </td> </tr> <tr> <td> <i> O.meridionalis </i> </td> <td> 101145, 101146, 101147, 101148, 101446, 105289 </td> <td> AA </td> </tr> <tr> <td> <i> O.minuta </i> </td> <td> IR21 101082, IR39 103865 </td> <td> BBCC </td> </tr> <tr> <td> <i> O.punctata </i> </td> <td> IR15 100886, IR43 105137 </td> <td> BB, BBCC </td> </tr> <tr> <td> <i> O.officinalis </i> </td> <td> IR55 105328 </td> <td> CC </td> </tr> <tr> <td> <i> O.alta </i> </td> <td> IR8 100161, IR47 105222 </td> <td> CCDD </td> </tr> <tr> <td> <i> O.grandiglumis </i> </td> <td> IR28 101405, IR60 105669 </td> <td> CCDD </td> </tr> <tr> <td> <i> O.latifolia </i> </td> <td> IR9 100172, IR45 105145 </td> <td> CCDD </td> </tr> <tr> <td> <i> O.australiensis </i> </td> <td> IR35 103303, IR51 105271 </td> <td> EE </td> </tr> </tbody> </table> </body> </html>

train

371,268

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train

21,527

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train

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train

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train

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train

428,701

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Total gene pairs </b> </td> <td> <b> Neighboring gene pairs </b> </td> <td> <b> Threshold for correlations </b> </td> <td> <b> Number of total gene pairs above the threshold </b> </td> <td> <b> Number of neighboring gene pairs above the threshold </b> </td> <td> <b> P-values based on the hypergeometric tests </b> </td> </tr> </thead> <tbody> <tr> <td> 18,797,646 </td> <td> 6,116 </td> <td> 0.5 </td> <td> 616,074 </td> <td> 752 </td> <td> 2.00e-008 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.6 </td> <td> 251,505 </td> <td> 401 </td> <td> 4.84e-009 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.7 </td> <td> 89,955 </td> <td> 196 </td> <td> 1.04e-008 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.8 </td> <td> 21,513 </td> <td> 68 </td> <td> 1.92e-008 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.9 </td> <td> 1,171 </td> <td> 13 </td> <td> 4.07e-009 </td> </tr> </tbody> </table> </body> </html>

train

473,978

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Total gene pairs sharing one regulator </b> </td> <td> <b> Gene pairs sharing one regulator and both are in the same deacetylation partition group </b> </td> <td> <b> Threshold for correlations </b> </td> <td> <b> Number of gene pairs sharing one regulator above the threshold </b> </td> <td> <b> Number of gene pairs sharing one regulator and both are in the same deacetylation partition group above the threshold </b> </td> <td> <b> P-values based on the hypergeometric tests </b> </td> </tr> </thead> <tbody> <tr> <td> 24,833 </td> <td> 141 </td> <td> 0.5 </td> <td> 4,676 </td> <td> 80 </td> <td> 3.43e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.6 </td> <td> 2,925 </td> <td> 54 </td> <td> 2.37e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.7 </td> <td> 1,519 </td> <td> 45 </td> <td> 2.24e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.8 </td> <td> 422 </td> <td> 20 </td> <td> 2.92e-011 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.9 </td> <td> 30 </td> <td> 3 </td> <td> 0.0000243 </td> </tr> <tr> <td> Total gene pairs sharing one regulator </td> <td> Gene pairs sharing one regulator and they belong to neighboring deacetylation partition groups </td> <td> Threshold for correlations </td> <td> Number of gene pairs sharing one regulator above the threshold </td> <td> Number of gene pairs sharing one regulator and they belong to neighboring deacetylation partition groups above the threshold </td> <td> P-values based on the hypergeometric tests </td> </tr> <tr> <td> 24,833 </td> <td> 46 </td> <td> 0.5 </td> <td> 4,676 </td> <td> 12 </td> <td> 0.0784 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.6 </td> <td> 2,925 </td> <td> 8 </td> <td> 0.0853 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.7 </td> <td> 1,519 </td> <td> 8 </td> <td> 0.00165 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.8 </td> <td> 422 </td> <td> 2 </td> <td> 0.0432 </td> </tr> <tr> <td> </td> <td> </td> <td> 0.9 </td> <td> 30 </td> <td> 0 </td> <td> 0.0541 </td> </tr> </tbody> </table> </body> </html>

train

190,675

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Primer name <sup> a </sup> </b> </td> <td> <b> Exon </b> </td> <td> <b> Sequence (5'-3') </b> </td> </tr> </thead> <tbody> <tr> <td> HGF1 </td> <td> 6 </td> <td> CATGAGAAGTATGACAACAGCCTC </td> </tr> <tr> <td> HGF2 </td> <td> 8 </td> <td> TGGTCTCCTCTGACTTCAAC </td> </tr> <tr> <td> HGR1 </td> <td> 9 </td> <td> GTTGCTGTAGCCAAATTCGTTGTC </td> </tr> <tr> <td> HGR2 </td> <td> 9 </td> <td> CTGTAGCCAAATTCGTTGTC </td> </tr> <tr> <td> HSF1 </td> <td> 4 </td> <td> CTACACTCTATGTGCGCAATCG </td> </tr> <tr> <td> HSF2 </td> <td> 1A </td> <td> TAGCAGTGTAGGTGGTTAGCAG </td> </tr> <tr> <td> HSF3 </td> <td> 1B </td> <td> GGGTCTAATTGACTTGAGAATGTG </td> </tr> <tr> <td> HSF4 </td> <td> 4 </td> <td> TTTTTGCATATACCCGCATAG </td> </tr> <tr> <td> HSF5 </td> <td> 1A-3 </td> <td> TCCTTCCTAGCAAGGGATG </td> </tr> <tr> <td> HSF6 </td> <td> 1B-3 </td> <td> AAAAAATTAAGCTGAAATGGATG </td> </tr> <tr> <td> HSR1 </td> <td> 6 </td> <td> TTTGGCTGCTAGTGTGACGTTG </td> </tr> <tr> <td> HSR2 </td> <td> 4 </td> <td> CTGATGCAAAGTATGAGCACAG </td> </tr> <tr> <td> HSR3 </td> <td> 4 </td> <td> CATTCCAGGCCCAGAGGAAAG </td> </tr> <tr> <td> HSR4 </td> <td> 5 </td> <td> CCCATATTACAATTCCAGAAG </td> </tr> <tr> <td> HSR5 </td> <td> 3 </td> <td> AAGTCTGCTTTCAAAATCCAG </td> </tr> <tr> <td> MGF </td> <td> 3 </td> <td> GTGGAGTCTACTGGTGTCTTC </td> </tr> <tr> <td> MGR </td> <td> 5 </td> <td> GTGGCAGTGATGGCATGGAC </td> </tr> <tr> <td> MSF1 </td> <td> 4 </td> <td> GATGCTATGAGTTTAGCACAACG </td> </tr> <tr> <td> MSF2 </td> <td> 1 </td> <td> ATGATGGAGATGCGAGTGGTAG </td> </tr> <tr> <td> MSR1 </td> <td> 5 </td> <td> CATCAGATGTCTCCTTACATGTC </td> </tr> <tr> <td> MSR2 </td> <td> 3 </td> <td> TGTGGTCTGTTTAGTATTAGATGC </td> </tr> <tr> <td> MSR3 </td> <td> 3 </td> <td> TTCCTTCTTACACACTGTGGTC </td> </tr> </tbody> </table> </body> </html>

train

125,676

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Level of Evidence </b> </td> <td> <b> Preventive Manoeuvre </b> </td> </tr> </thead> <tbody> <tr> <td> <b> A <sup> Ω </sup> & B <sup> ¥ </sup> -categories </b> : (Appropriate) </td> <td> 1. Folic acid for primary prevention of neural tube defects </td> </tr> <tr> <td> </td> <td> 2. Smoking cessation and nicotine replacement </td> </tr> <tr> <td> </td> <td> 3. Treatment for Hypertension </td> </tr> <tr> <td> </td> <td> 4. Mammography and exam in women over 50 </td> </tr> <tr> <td> </td> <td> 5. STD screening for high risk groups </td> </tr> <tr> <td> </td> <td> 6. Papanicolaou smears for sexually active women </td> </tr> <tr> <td> </td> <td> 7. Influenza vaccination to patients 65 and older </td> </tr> <tr> <td> </td> <td> 8. Blood pressure measurement for patients 21 to 64 years of age </td> </tr> <tr> <td> <b> D <sup> ψ </sup> - category: </b> (Inappropriate) </td> <td> 1. Proteinuria screening for general population </td> </tr> <tr> <td> </td> <td> 2. Blood glucose for the general population </td> </tr> <tr> <td> </td> <td> 3. Prostate-specific antigen testing for men over 50 </td> </tr> <tr> <td> </td> <td> 4. Chest radiography </td> </tr> <tr> <td> </td> <td> 5. Mammography in women under 50 </td> </tr> </tbody> </table> </body> </html>

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train

96,092

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Cost Item </b> </td> <td> <b> 1999 Dollars </b> </td> </tr> </thead> <tbody> <tr> <td> Staff training </td> <td> $20,450 </td> </tr> <tr> <td> Salaries & Benefits </td> <td> $178,200 </td> </tr> <tr> <td> Supplies </td> <td> $7,060 </td> </tr> <tr> <td> Telephone </td> <td> $8,629 </td> </tr> <tr> <td> Car Mileage & Insurance </td> <td> $12,049 </td> </tr> <tr> <td> Supervision </td> <td> $12,000 </td> </tr> <tr> <td> INTERVENTION COST </td> <td> $238,388 </td> </tr> </tbody> </table> </body> </html>

train

246,583

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train

120,280

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train

283,146

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Registration </b> </td> <td colspan="2"> <b> Priority 1 </b> </td> <td colspan="2"> <b> Priority 2 </b> </td> <td colspan="2"> <b> Priority 3 </b> </td> </tr> </thead> <tbody> <tr> <td> <b> period </b> </td> <td> <b> N </b> </td> <td> <b> (%) </b> </td> <td> <b> N </b> </td> <td> <b> (%) </b> </td> <td> <b> N </b> </td> <td> <b> (%) </b> </td> </tr> <tr> <td> 1991–1992 </td> <td> 116 </td> <td> (6.7) </td> <td> 1221 </td> <td> (70.8) </td> <td> 334 </td> <td> (19.4) </td> </tr> <tr> <td> 1993–1994 </td> <td> 110 </td> <td> (5.8) </td> <td> 1381 </td> <td> (73.1) </td> <td> 388 </td> <td> (20.5) </td> </tr> <tr> <td> 1995–1996 </td> <td> 249 </td> <td> (12.4) </td> <td> 1363 </td> <td> (67.8) </td> <td> 374 </td> <td> (18.6) </td> </tr> <tr> <td> 1997–1998 </td> <td> 117 </td> <td> (6.2) </td> <td> 1327 </td> <td> (70.3) </td> <td> 428 </td> <td> (22.7) </td> </tr> <tr> <td> 1999–2000 </td> <td> 67 </td> <td> (3.9) </td> <td> 1204 </td> <td> (70.0) </td> <td> 439 </td> <td> (25.5) </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Registration period </b> </td> <td> <b> Number of operations </b> </td> <td> <b> Total wait time, weeks </b> </td> <td> <b> Crude Rate, per 100 </b> </td> <td> <b> SE </b> </td> <td> <b> Hazard ratio </b> </td> <td> <b> 95% CI* </b> </td> </tr> </thead> <tbody> <tr> <td> 1991–1992 </td> <td> 1504 </td> <td> 23047 </td> <td> 6.5 </td> <td> 0.2 </td> <td> 1.00 </td> <td> referent </td> </tr> <tr> <td> 1993–1994 </td> <td> 1646 </td> <td> 25480 </td> <td> 6.5 </td> <td> 0.2 </td> <td> 1.00 </td> <td> 0.93, 1.08 </td> </tr> <tr> <td> 1995–1996 </td> <td> 1727 </td> <td> 34186 </td> <td> 5.1 </td> <td> 0.1 </td> <td> 0.70 </td> <td> 0.65, 0.76 </td> </tr> <tr> <td> 1997–1998 </td> <td> 1613 </td> <td> 30384 </td> <td> 5.3 </td> <td> 0.1 </td> <td> 0.77 </td> <td> 0.71, 0.83 </td> </tr> <tr> <td> 1999–2000 </td> <td> 1501 </td> <td> 24029 </td> <td> 6.2 </td> <td> 0.2 </td> <td> 0.94 </td> <td> 0.88, 1.02 </td> </tr> <tr> <td> All periods </td> <td> 7991 </td> <td> 137126 </td> <td> 5.8 </td> <td> 0.1 </td> <td> - </td> <td> - </td> </tr> </tbody> </table> </body> </html>

train

319,918

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> Hospital admissions </b> </td> <td> <b> ER admissions </b> </td> <td> <b> Specialist visits </b> </td> <td> <b> GP visits </b> </td> <td> <b> <i> P </i> </b> </td> </tr> </thead> <tbody> <tr> <td> resources used, n </td> <td> 29 </td> <td> 31 </td> <td> 74 </td> <td> 42 </td> <td> </td> </tr> <tr> <td> patients, n (%) </td> <td> 25 (19.2) </td> <td> 29 (22.3) </td> <td> 54 (41.5) </td> <td> 35 (26.9) </td> <td> </td> </tr> <tr> <td> resources/patient, mean (range) </td> <td> 1.2 (1–3) </td> <td> 1.1 (1–2) </td> <td> 1.4 (1–3) </td> <td> 1.2 (1–3) </td> <td> </td> </tr> <tr> <td> patient characteristics </td> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> age (years) </td> <td> 71.0 ± 9.4 (45–86) </td> <td> 68.1 ± 9.0 (47–83) </td> <td> 68.6 ± 9.1 (45–85) </td> <td> 72.9 ± 7.7 (54–85) </td> <td> Ns </td> </tr> <tr> <td> age at onset of PD (years) </td> <td> 64.3 ± 9.4 (40–84) </td> <td> 58.7 ± 7.3* (42–72) </td> <td> 62.0 ± 8.6 (40–80) </td> <td> 64.1 ± 7.5 (50–78) </td> <td> 0.037 </td> </tr> <tr> <td> PD duration (years) </td> <td> 6.7 ± 3.5 (2–20) </td> <td> 9.4 ± 3.8 <sup> # </sup> (2–20) </td> <td> 6.6 ± 3.7 (1–24) </td> <td> 8.8 ± 4.6 (1–24) </td> <td> 0.004 </td> </tr> <tr> <td> H&Y stage </td> <td> 2.8 ± 0.9 (I-IV) </td> <td> 3.0 ± 1.0 (I-IV) </td> <td> 2.5 ± 1.0 (I-IV) </td> <td> 3.0 ± 1.0 (I-IV) </td> <td> Ns </td> </tr> </tbody> </table> </body> </html>

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train

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train

31,064

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td colspan="4"> <b> Mouse RAMP-1 transcriptional start sites </b> </td> </tr> </thead> <tbody> <tr> <td> Clone </td> <td> Brain </td> <td> Muscle </td> <td> Heart </td> </tr> <tr> <td> 1 </td> <td> -41 </td> <td> -50 </td> <td> -41 </td> </tr> <tr> <td> 2 </td> <td> -41 </td> <td> -50 </td> <td> -41 </td> </tr> <tr> <td> 3 </td> <td> -41 </td> <td> -40 </td> <td> -41 </td> </tr> <tr> <td> 4 </td> <td> -9 </td> <td> -40 </td> <td> -9 </td> </tr> <tr> <td> 5 </td> <td> -9 </td> <td> -50 </td> <td> -35 </td> </tr> <tr> <td> 6 </td> <td> -11 </td> <td> -35 </td> <td> -35 </td> </tr> <tr> <td> 7 </td> <td> -50 </td> <td> -9 </td> <td> -9 </td> </tr> <tr> <td> 8 </td> <td> -41 </td> <td> -11 </td> <td> -50 </td> </tr> <tr> <td> 9 </td> <td> -50 </td> <td> - </td> <td> -41 </td> </tr> <tr> <td> 10 </td> <td> -35 </td> <td> - </td> <td> - </td> </tr> </tbody> </table> </body> </html>

train

142,278

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Genotype </b> </td> <td> <b> Affected subjects (n = 76) </b> </td> <td> <b> Ethnic affiliation </b> </td> </tr> </thead> <tbody> <tr> <td colspan="3"> Mutations </td> </tr> <tr> <td> 35delG / 35delG </td> <td> 7 (4 independent families) </td> <td> Russians </td> </tr> <tr> <td> 235delC / 235delC </td> <td> 1 </td> <td> Altaian </td> </tr> <tr> <td> 312del14 / 312del14 </td> <td> 1 </td> <td> Russian/Tatar </td> </tr> <tr> <td> 35delG / 235delC </td> <td> 2 (unrelated) </td> <td> 1 – Russian/Altaian, 1 – Russian </td> </tr> <tr> <td> 35delG / 312del14 </td> <td> 1 </td> <td> Russian </td> </tr> <tr> <td> R75Q <sup> a </sup> / 235delC </td> <td> 1 </td> <td> Altaian/Russian </td> </tr> <tr> <td> R75Q / 312del14 </td> <td> 2 (two sibs) </td> <td> mixed ethnicity </td> </tr> <tr> <td> R75Q/ + </td> <td> 2 (father and daughter) </td> <td> Russians </td> </tr> <tr> <td> 235delC / W172C </td> <td> 1 </td> <td> Altaian </td> </tr> <tr> <td> Total </td> <td colspan="2"> 18 (23.7%) </td> </tr> <tr> <td colspan="3"> Non-pathogenic variants </td> </tr> <tr> <td> V27I / + </td> <td> 14 (11 independent families) </td> <td> 13 Altaians, 1 Kazakh </td> </tr> <tr> <td> (V27I; E114G) <sup> b </sup> </td> <td> 7 (unrelated) </td> <td> 6 Altaians, 1 Altaian/Russian <sup> c </sup> </td> </tr> <tr> <td> IVS1+27G>C / [V27I; E114G] </td> <td> 1 </td> <td> Altaian </td> </tr> <tr> <td> Total </td> <td colspan="2"> 22 (28.9%) </td> </tr> </tbody> </table> </body> </html>

train

166,847

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Haplotype <sup> a </sup> </b> </td> <td> <b> Patient </b> </td> <td> <b> Normal </b> </td> <td> <b> Fisher's Exact Test ( <i> P </i> value) <sup> b </sup> </b> </td> <td> <b> OR <sup> b,c,d </sup> </b> </td> <td> <b> 95% CI <sup> d </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> <b> TAGTAAGACA </b> </td> <td> 0.340 </td> <td> 0.359 </td> <td> 0.755 </td> <td> 0.919 </td> <td> 0.61–1.38 </td> </tr> <tr> <td> <b> TAGAGACCTG </b> </td> <td> 0.145 </td> <td> 0.140 </td> <td> 1.000 </td> <td> 1.035 </td> <td> 0.59–1.80 </td> </tr> <tr> <td> <b> GGTTGCCCTA </b> </td> <td> 0.095 </td> <td> 0.068 </td> <td> 0.366 </td> <td> 1.439 </td> <td> 0.70–2.96 </td> </tr> <tr> <td> <b> TAGTAACACA </b> </td> <td> 0.010 </td> <td> 0.039 </td> <td> 0.105 </td> <td> 0.250 </td> <td> 0.05–1.19 </td> </tr> <tr> <td> <b> TAGTAAGATA </b> </td> <td> 0.025 </td> <td> 0.010 </td> <td> 0.278 </td> <td> 2.615 </td> <td> 0.50–13.64 </td> </tr> <tr> <td> <b> TAGTGCGACA </b> </td> <td> 0.025 </td> <td> 0.015 </td> <td> 0.498 </td> <td> 1.735 </td> <td> 0.41–7.36 </td> </tr> <tr> <td> <b> GGGAGACCCA </b> </td> <td> 0.025 </td> <td> 0 </td> <td> 0.028 </td> <td> -- </td> <td> -- </td> </tr> <tr> <td> <b> TAGTAACCTG </b> </td> <td> 0.020 </td> <td> 0 </td> <td> 0.058 </td> <td> -- </td> <td> -- </td> </tr> <tr> <td> <b> TAGTGACCTG </b> </td> <td> 0.020 </td> <td> 0.010 </td> <td> 0.443 </td> <td> 2.081 </td> <td> 0.38–11.49 </td> </tr> <tr> <td> <b> TAGAGACATG </b> </td> <td> 0.020 </td> <td> 0.019 </td> <td> 1.000 </td> <td> 1.031 </td> <td> 0.25–4.18 </td> </tr> <tr> <td> <b> GGTTGCCCTG </b> </td> <td> 0.020 </td> <td> 0.010 </td> <td> 0.443 </td> <td> 2.082 </td> <td> 0.38–11.49 </td> </tr> <tr> <td> <b> GGTAGACCCA </b> </td> <td> 0.015 </td> <td> 0.024 </td> <td> 0.724 </td> <td> 0.612 </td> <td> 0.14–2.59 </td> </tr> <tr> <td> <b> Others </b> </td> <td> 0.240 </td> <td> 0.306 </td> <td> 0.149 </td> <td> 0.717 </td> <td> 0.46–1.11 </td> </tr> <tr> <td> Total </td> <td> </td> <td> </td> <td> 0.082 </td> <td> </td> <td> </td> </tr> <tr> <td> <b> <i> P </i> value of permutation test </b> </td> <td> <b> 0.602 </b> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> </tbody> </table> </body> </html>

train

498,299

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Haplotypes from htSNPs <sup> a </sup> </b> </td> <td> <b> Represented haplotypes from 10 SNPs <sup> a </sup> </b> </td> <td> <b> Patient (frequency) </b> </td> <td> <b> Normal </b> </td> <td> <b> Fisher's Exact Test ( <i> P </i> value) <sup> b </sup> </b> </td> <td> <b> OR <sup> a,c </sup> </b> </td> <td> <b> 95% CI <sup> c </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> <b> TAG </b> </td> <td> <b> TAGTAAGACA </b> <b> TAGTAAGATA </b> </td> <td> 0.365 </td> <td> 0.369 </td> <td> 1.000 </td> <td> 0.983 </td> <td> 0.66–1.47 </td> </tr> <tr> <td> <b> TGC </b> </td> <td> <b> TAGAGACCTG </b> <b> TAGTGACCTG </b> <b> TAGTGACATG </b> </td> <td> 0.185 </td> <td> 0.169 </td> <td> 0.699 </td> <td> 1.109 </td> <td> 0.66–1.85 </td> </tr> <tr> <td> <b> GGC </b> </td> <td> <b> GGTTGCCCTA </b> <b> GGGAGACCCA </b> <b> GGTTGCCCTG </b> <b> GGTAGACCCA </b> </td> <td> 0.155 </td> <td> 0.102 </td> <td> 0.137 </td> <td> 1.616 </td> <td> 0.89–2.92 </td> </tr> <tr> <td> <b> TAC </b> </td> <td> <b> TAGTAACACA </b> <b> TAGTAACCTG </b> </td> <td> 0.030 </td> <td> 0.039 </td> <td> 0.787 </td> <td> 0.765 </td> <td> 0.26–2.25 </td> </tr> <tr> <td> <b> TGG </b> </td> <td> <b> TAGCGCGACA </b> </td> <td> 0.025 </td> <td> 0.015 </td> <td> 0.498 </td> <td> 1.735 </td> <td> 0.41–7.36 </td> </tr> <tr> <td> <b> Others </b> </td> <td> </td> <td> 0.240 </td> <td> 0.306 </td> <td> 0.149 </td> <td> 0.717 </td> <td> 0.46–1.11 </td> </tr> <tr> <td> <b> Total </b> </td> <td> </td> <td> </td> <td> </td> <td> 0.446 </td> <td> </td> <td> </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Search term OVID search* </b> </td> <td> <b> Sensitivity (n = 97) </b> </td> <td> <b> Specificity (n = 27672) </b> </td> <td> <b> Precision† </b> </td> <td> <b> Accuracy (n = 27769) </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Best sensitivity </b> (keeping specificity ≥ 50%)di.fs. </td> <td> 91.8 (86.3 to 97.2) </td> <td> 76.4 (75.9 to 76.9) </td> <td> 1.4 (1.1 to 1.6) </td> <td> 76.5 (76.0 to 77.0) </td> </tr> <tr> <td> <b> Best specificity </b> (keeping sensitivity ≥ 50%)specificity.tw. </td> <td> 62.9 (53.5 to 72.5) </td> <td> 98.2 (98.1 to 98.4) </td> <td> 11.0 (8.4 to 13.6) </td> <td> 98.1 (97.9 to 98.3) </td> </tr> <tr> <td> <b> Best Optimization of Sensitivity & Specificity‡ </b> diagnos:.mp. </td> <td> 89.7 (83.6 to 95.7) </td> <td> 84.7 (84.3 to 85.2) </td> <td> 2.0 (1.6 to 2.4) </td> <td> 84.8 (84.3 to 85.2) </td> </tr> </tbody> </table> </body> </html>

train

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train

278,596

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train

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> Gilad </b> </td> <td> <b> Gray </b> </td> <td> <b> TK </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Primer sequences </b> </td> <td> 5'-GACGACGCCGGA GACCTTGTG-3'5'-CACAAGTTCAGTCT GTTCCTCAAC-3' </td> <td> 5'-GACACCACATCTGCAA GGAG-3'5'-GACACATGTTACAAT GGTGGC-3' </td> <td> 5'-GGGTTACCTGTACGAG-3'5'-CACCCAGTAGAT TATGC-3' </td> </tr> <tr> <td> <b> Fragment size </b> </td> <td> 484 bp </td> <td> 290 bp </td> <td> 409 bp </td> </tr> <tr> <td> <b> Enzyme </b> </td> <td> 1 unit Taq DNA polymerase platinum (Invitrogen) </td> <td> 1 unit Taq DNA polymerase (Promega) </td> <td> 1 unit Taq DNA polymerase platinum (Invitrogen) </td> </tr> <tr> <td> <b> Reaction buffer </b> </td> <td> *Tris-HCl 20 nM pH = 8.4KCl 50 mMMgCl <sub> 2 </sub> 2 mM(NH <sub> 4 </sub> ) <sub> 2 </sub> SO <sub> 4 </sub> 15 mM*Taq platinum buffer </td> <td> Tris-HCl 60 nM pH = 8.3MgCl <sub> 2 </sub> 2 mM(NH <sub> 4 </sub> ) <sub> 2 </sub> SO <sub> 4 </sub> 15 mM </td> <td> *Tris-HCl 20 nM pH = 8.4KCl 50 mMMgCl <sub> 2 </sub> 1.5 mM*Taq platinum buffer </td> </tr> <tr> <td> <b> Primers / dNTP's </b> </td> <td> 30 pmole /reaction 400 μM </td> <td> 0.25 μg/reaction 10 μM </td> <td> 0.4 μg/reaction 200 μM </td> </tr> <tr> <td> <b> DNA concentration </b> </td> <td> 157 ng/reaction) </td> <td> 157 ng/reaction </td> <td> 157 ng/reaction </td> </tr> <tr> <td> <b> PCR reaction volume </b> </td> <td> 50 μl </td> <td> 50 μl </td> <td> 50 μl </td> </tr> <tr> <td> <b> Program </b> </td> <td> 95°c for 5 min94°c for 1 min68°c for 1 min72°c for 30 sec39 cycles72 C for 7 min </td> <td> 94°c for 1 min55°c for 2 min72°c for 3 min30 cycles72°c for 7 min </td> <td> 95°c 5 min95°c 30 sec52°c 30 sec72°c 1 min35 cycles72°c for 10 min </td> </tr> <tr> <td> <b> PCR apparatus </b> </td> <td> Biometra -T Gradient </td> <td> Biometra -T Gradient </td> <td> Biometra -T Gradient </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Sample </b> </td> <td> <b> TK PCR </b> </td> <td> <b> Gilad PCR </b> </td> <td> <b> Gray PCR </b> </td> <td> <b> Virus Isolation </b> </td> <td> <b> History of the koi carp </b> </td> </tr> </thead> <tbody> <tr> <td> 1 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> sick fish with clinical symptoms </td> </tr> <tr> <td> 2 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor (unknown time lap after exposure). </td> </tr> <tr> <td> 3 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor (unknown time lap after exposure) from a tank with mortality. </td> </tr> <tr> <td> 4 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor (unknown time lap after exposure) from a tank with mortality. </td> </tr> <tr> <td> 5 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor moved to 30°C, then to 24°C. no mortality in the tank. </td> </tr> <tr> <td> 6 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor moved to 30°C, then moved to 24°C. 25% mortality in the tank. </td> </tr> <tr> <td> 7 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> naïve fish that lived at 16°C. No mortality in the tank. </td> </tr> <tr> <td> 8 </td> <td> + </td> <td> + </td> <td> + </td> <td> + </td> <td> fish from tank with mortality. </td> </tr> <tr> <td> 9 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> fish from tank with mortality. </td> </tr> <tr> <td> 10 </td> <td> - </td> <td> - </td> <td> - </td> <td> Pooled </td> <td> survivor, 2 years after experimental infection </td> </tr> <tr> <td> 11 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor, 2 years after experimental infection </td> </tr> <tr> <td> 12 </td> <td> - </td> <td> - </td> <td> - </td> <td> Pooled </td> <td> survivor, 1 year after experimental infection </td> </tr> <tr> <td> 13 </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> survivor, 1 year after experimental infection </td> </tr> <tr> <td> 14 </td> <td> - </td> <td> - </td> <td> - </td> <td> Pooled </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 15 </td> <td> - </td> <td> - </td> <td> - </td> <td> </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 16 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 17 </td> <td> + </td> <td> - </td> <td> - </td> <td> </td> <td> survivor, 2 months after experimental infection </td> </tr> <tr> <td> 18 </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> survivor from tank with disease- two weeks post infection. </td> </tr> <tr> <td> KF+ </td> <td> + </td> <td> + </td> <td> + </td> <td> + </td> <td> KF-1 cell line infected with KHV- Positive control. </td> </tr> <tr> <td> KF- </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> KF-1 cell line- Negative control. </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> <i> Sph </i> I </b> </td> <td> <b> <i> Nco </i> I </b> </td> <td> <b> <i> Nhe </i> I </b> </td> <td> <b> <i> Ssp </i> I </b> </td> <td> <b> <i> Sfu </i> I </b> </td> <td> <b> <i> Eco </i> RV </b> </td> <td> <b> <i> Dra </i> I </b> </td> <td> <b> <i> Vsp </i> I </b> </td> <td> <b> <i> Hinc </i> II </b> </td> <td> <b> <i> Eco </i> RI </b> </td> <td> <b> <i> Hind </i> III </b> </td> </tr> </thead> <tbody> <tr> <td> <i> Lact. delbrueckii </i> </td> <td> - <sup> a </sup> </td> <td> + <sup> a </sup> </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. amylolyticus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. acidophilus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. amylovorus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. helveticus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. crispatus </i> </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> </tr> <tr> <td> <i> Lact. perolens </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. gasseri </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. johnsonii </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. jensenii </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. reuterii </i> </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. vaginalis </i> </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> ++ <sup> b </sup> </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. brevis </i> </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. sakei </i> </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> ++ </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. casei </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. rhamnosus </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> </tr> <tr> <td> <i> Lact. salivarius </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> ++ </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. ruminis </i> </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. plantarum a </i> </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> - <sup> c </sup> </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. plantarum b </i> </td> <td> + </td> <td> - </td> <td> - </td> <td> + </td> <td> + <sup> c </sup> </td> <td> - </td> <td> - </td> <td> + </td> <td> + </td> <td> - </td> <td> - </td> </tr> <tr> <td> <i> Lact. fermentum </i> </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> - </td> <td> + </td> <td> - </td> <td> - </td> <td> - </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Culture conditions </b> </td> <td colspan="2"> <b> CYP110-gold conjugates </b> </td> </tr> <tr> <td> </td> <td colspan="2"> <b> (Avg. no. of gold particles) </b> </td> </tr> <tr> <td> </td> <td> <b> Vegetative cell </b> </td> <td> <b> Heterocyst cell </b> </td> </tr> </thead> <tbody> <tr> <td> <i> Anabaena </i> 7120 untreated </td> <td> 8 </td> <td> 5 </td> </tr> <tr> <td> <i> Anabaena </i> 7120 dodecane treatment </td> <td> 22 </td> <td> 5 </td> </tr> <tr> <td> <i> Anabaena </i> 7120 hexadecane treatment </td> <td> 50 </td> <td> 5 </td> </tr> </tbody> </table> </body> </html>

train

111,448

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train

34,330

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Enzyme name </b> </td> <td> <b> Potential Inhibitor </b> </td> <td> <b> Prior testing? </b> </td> <td> <b> Reference </b> </td> </tr> </thead> <tbody> <tr> <td> acetyl-CoA carboxylase </td> <td> pseudopeptide pyrrolidine dione antibiotics </td> <td> SA, B </td> <td> [45] </td> </tr> <tr> <td> 4-amino-4-deoxychorismate synthase </td> <td> (6s)-6-fluoroshikimate </td> <td> B </td> <td> [46] </td> </tr> <tr> <td> Adenosylmethionine decarboxylase </td> <td> CGP 40215A, AdoMao </td> <td> B </td> <td> [47,48] </td> </tr> <tr> <td> asparagine synthase (glutamine-hydrolysing) </td> <td> mucochloric and mucobromic acids, L-cysteine sulfinic acid </td> <td> B </td> <td> [49,50] </td> </tr> <tr> <td> dihydrofolate reductase </td> <td> methylpteridines </td> <td> B </td> <td> [51] </td> </tr> <tr> <td> dihydropteroate synthase </td> <td> Sulfone and sulfanilamide sulfa drugs </td> <td> B </td> <td> [52,53] </td> </tr> <tr> <td> 3-dehydroquinate synthase </td> <td> carbocyclic inhibitors </td> <td> B </td> <td> [54] </td> </tr> <tr> <td> FMN adenylyltransferase (FAD synthase) </td> <td> Riboflavin 5'-pyrophosphate </td> <td> F </td> <td> [55] </td> </tr> <tr> <td> glycerol-3-phosphate dehydrogenase (NADP) </td> <td> 5-n-alk(en)ylresorcinols </td> <td> NF </td> <td> [56] </td> </tr> <tr> <td> glutamine synthetase </td> <td> L-methionine sulfoximine, aminomethylene-bisphosphonic acid derivatives </td> <td> NF </td> <td> [57,58] </td> </tr> <tr> <td> glutamyl-tRNA reductase </td> <td> see table I in paper </td> <td> NF </td> <td> [59] </td> </tr> <tr> <td> GTP cyclohydrolase I </td> <td> Diamino-6-hydroxypyrimidine, pterins </td> <td> NF </td> <td> [60,61] </td> </tr> <tr> <td> Hydroxymethylglutaryl CoA reductase (ir) </td> <td> statins </td> <td> NF </td> <td> [62,63] </td> </tr> <tr> <td> Hydroxymethylglutaryl CoA synthase (ir) </td> <td> beta-lactone, 3-Hydroxy-3-methylglutaryldithio-coenzyme A </td> <td> NF </td> <td> [64,65] </td> </tr> <tr> <td> isopentenyl-diphosphate D-isomerase </td> <td> NE21650 </td> <td> NF </td> <td> [66] </td> </tr> <tr> <td> methionine adenosyltransferase </td> <td> adduncts 14 and 16 </td> <td> B </td> <td> [67] </td> </tr> <tr> <td> Phosphatidate phosphatase </td> <td> Propranolol </td> <td> NF </td> <td> [68] </td> </tr> <tr> <td> phosphoribosylpyrophosphate synthetase </td> <td> MRPP, ARPP </td> <td> NF </td> <td> [69] </td> </tr> <tr> <td> riboflavin synthase </td> <td> 9-D-ribitylamino-1,3,7,9-tetrahydro-2,6,8-purinetriones </td> <td> B </td> <td> [70] </td> </tr> <tr> <td> spermidine synthase </td> <td> adenosylspermidine, dicyclohexylamine </td> <td> SA, B </td> <td> [71,72] </td> </tr> <tr> <td> thiamine transport via ABC system </td> <td> azidobenzoyl derivatives of thiamin, methylene blue </td> <td> F </td> <td> [73,74] </td> </tr> <tr> <td> thioredoxin reductase </td> <td> Arsenicals, Aurothioglucose </td> <td> NF </td> <td> [75,76] </td> </tr> <tr> <td> UDP-N-acetylglucosamine 4-epimerase </td> <td> uridine analogs </td> <td> NF </td> <td> [77] </td> </tr> <tr> <td> UDP-N-acetylenolpyruvoylglucosamine reductase </td> <td> 4-thiazolidinones </td> <td> B </td> <td> [78] </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Search Step </b> </td> <td> <b> <i> ask </i> MEDLINE exact match retrieved/total questions (% total) </b> </td> <td> <b> Entrez PubMed exact match retrieved/total questions (% total) </b> </td> </tr> </thead> <tbody> <tr> <td> A. Match at first pass </td> <td> 59/95 (62.1) </td> <td> 13/95 (13.7) </td> </tr> <tr> <td> B. Match after a related citation search </td> <td> 11/95 (11.6) </td> <td> 8/95 (8.4) </td> </tr> <tr> <td> C. Match after question rephrase </td> <td> 2/95 (2.1) </td> <td> 0/95 (0) </td> </tr> <tr> <td> <b> Total exact match after A, B, and C </b> </td> <td> <b> 75.8% </b> </td> <td> <b> 22.1 </b> </td> </tr> <tr> <td> No match after A, B, and C, but relevant articles retrieved </td> <td> 20/95 (21) </td> <td> 16/95 (16.8) </td> </tr> <tr> <td> <b> Overall efficiency </b> </td> <td> <b> 96.8% </b> </td> <td> <b> 38.9% </b> </td> </tr> <tr> <td> Citations retrieved, but not matched or relevant </td> <td> 3/95 (3.1) </td> <td> 6/95 (6.3) </td> </tr> <tr> <td> No citations retrieved </td> <td> 0/95 (0) </td> <td> 52/95 (54.7) </td> </tr> <tr> <td> <b> Overall retrieval failure </b> </td> <td> <b> 3.1% </b> </td> <td> <b> 61% </b> </td> </tr> </tbody> </table> </body> </html>

train

276,034

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> <underline> Problems </underline> </b> </td> <td> <b> <underline> Interventions </underline> </b> </td> <td> <b> <underline> Reference </underline> </b> </td> </tr> </thead> <tbody> <tr> <td> Alzheimer's disease </td> <td> Galantamine </td> <td> 8 </td> </tr> <tr> <td> Bulimia </td> <td> Antidepressants versus psychological treatment versus both </td> <td> 9 </td> </tr> <tr> <td> Jet lag </td> <td> Melatonin </td> <td> 10 </td> </tr> <tr> <td> Lumbar disc prolapse </td> <td> Surgery </td> <td> 11 </td> </tr> <tr> <td> Malaria prevention </td> <td> Mefloquine </td> <td> 12 </td> </tr> <tr> <td> Nausea and vomiting in early pregnancy </td> <td> Treatments </td> <td> 13,14* </td> </tr> <tr> <td> Schizophrenia </td> <td> Haloperidol </td> <td> 15 </td> </tr> <tr> <td> Vaginal yeast infection </td> <td> Oral versus intravaginal antifungal agents </td> <td> 16 </td> </tr> </tbody> </table> </body> </html>

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> Amputated </b> </td> <td> <b> Revascularized </b> </td> </tr> <tr> <td> <b> N = 3942 </b> </td> <td> <b> N = 2046 </b> </td> <td> <b> N= 1896 </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Demographics </b> </td> <td> </td> <td> </td> </tr> <tr> <td> Age in years, mean ± SD </td> <td> 69.4 ± 9.7 </td> <td> 71.5 ± 8.1 </td> </tr> <tr> <td> Male Gender, n (%) </td> <td> 1148 (56) </td> <td> 1097 (58) </td> </tr> <tr> <td> Race, n (%) </td> <td> </td> <td> </td> </tr> <tr> <td> Caucasians </td> <td> 1333 (65) </td> <td> 1464 (77) </td> </tr> <tr> <td> African Americans </td> <td> 630 (31) </td> <td> 370(20) </td> </tr> <tr> <td> Other </td> <td> 83 (4) </td> <td> 62 (3) </td> </tr> <tr> <td> <b> ESRD </b> </td> <td> </td> <td> </td> </tr> <tr> <td> Diabetes as cause of ESRD, n (%) </td> <td> 1518 (74) </td> <td> 1011 (53) </td> </tr> <tr> <td> Dialysis Modality, n (%) </td> <td> </td> <td> </td> </tr> <tr> <td> HD </td> <td> 1875 (92) </td> <td> 1777 (94) </td> </tr> <tr> <td> PD </td> <td> 171 (8) </td> <td> 119 (6) </td> </tr> <tr> <td> <b> Comorbidity </b> </td> <td> </td> <td> </td> </tr> <tr> <td> Coronary disease, n (%) </td> <td> 1077 (53) </td> <td> 893 (47) </td> </tr> <tr> <td> Congestive heart failure, n (%) </td> <td> 1076 (53) </td> <td> 934 (49) </td> </tr> <tr> <td> Cerebrovascular disease, n (%) </td> <td> 380 (19) </td> <td> 289 (15) </td> </tr> <tr> <td> Smoker, n (%) </td> <td> 94 (5) </td> <td> 138 (7) </td> </tr> <tr> <td> Cancer, n (%) </td> <td> 74 (4) </td> <td> 91 (5) </td> </tr> <tr> <td> <b> Clinical Indications </b> </td> <td> </td> <td> </td> </tr> <tr> <td> Intermittent claudication </td> <td> 6 (0.3) </td> <td> 91 (4.8) </td> </tr> <tr> <td> Resting pain </td> <td> 13 (0.6) </td> <td> 97 (5.1) </td> </tr> <tr> <td> Ulcer </td> <td> 31 (1.5) </td> <td> 225 (11.9) </td> </tr> <tr> <td> Gangrene </td> <td> 1850 (90.4) </td> <td> 755 (39.8) </td> </tr> <tr> <td> Other/unknown </td> <td> 146 (7.1) </td> <td> 728 (38.4) </td> </tr> <tr> <td> <b> Nutrition </b> </td> <td> </td> <td> </td> </tr> <tr> <td> BMI, mean ± SD </td> <td> 25.3 ± 5.6 </td> <td> 24.7 ± 5.2 </td> </tr> <tr> <td> Serum Albumin, mean ± SD </td> <td> 3.0 ± 0.6 </td> <td> 3.2 ± 0.6 </td> </tr> <tr> <td> <b> Functional Status </b> </td> <td> </td> <td> </td> </tr> <tr> <td> Require assistance to transfer, n (%) </td> <td> 139 (7) </td> <td> 30 (2) </td> </tr> <tr> <td> Require assistance to ambulate, n (%) </td> <td> 342 (17) </td> <td> 113 (6) </td> </tr> <tr> <td> <b> Other </b> </td> <td> </td> <td> </td> </tr> <tr> <td> Hematocrit, mean ± SD </td> <td> 27.8 ± 7.0 </td> <td> 28.5 (6.8) </td> </tr> </tbody> </table> </body> </html>

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> 30 day mortality </b> </td> <td> <b> 1 year mortality </b> </td> </tr> <tr> <td> </td> <td> <b> Odds ratio* (95%CI) </b> </td> <td> <b> Odds ratio* (95%CI) </b> </td> </tr> </thead> <tbody> <tr> <td> Entire cohort (n = 3942) </td> <td> </td> <td> </td> </tr> <tr> <td> Unadjusted </td> <td> 2.00 (1.64–2.44) </td> <td> 1.67 (1.48–1.90) </td> </tr> <tr> <td> Adjusted** </td> <td> 1.85 (1.45–2.36) </td> <td> 1.46 (1.25–1.71) </td> </tr> <tr> <td> Subgroup analyses by likelihood for amputation*** </td> <td> </td> <td> </td> </tr> <tr> <td> Low likelihood group (n = 1314) </td> <td> 1.85 (1.06–3.23) </td> <td> 1.61 (1.14–2.26) </td> </tr> <tr> <td> Moderate likelihood group (n = 1314) </td> <td> 2.05 (1.47–2.87) </td> <td> 1.55 (1.22–1.96) </td> </tr> <tr> <td> High likelihood group (n = 1314) </td> <td> 1.56 (0.91–2.21) </td> <td> 1.23 (0.92–1.63) </td> </tr> </tbody> </table> </body> </html>

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td colspan="4"> <b> Logistic regression confusion matrix </b> </td> </tr> </thead> <tbody> <tr> <td> </td> <td colspan="2"> Predicted </td> <td> </td> </tr> <tr> <td> Actual </td> <td> DBA/2J </td> <td> C57BL/6J </td> <td> Total </td> </tr> <tr> <td> DBA/2J </td> <td> 15 </td> <td> 1 </td> <td> 16 </td> </tr> <tr> <td> C57BL/6J </td> <td> 2 </td> <td> 12 </td> <td> 14 </td> </tr> <tr> <td> Total </td> <td> 17 </td> <td> 13 </td> <td> 30 </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td colspan="2"> <b> Nuclear Eccentricity (%) <sup> a </sup> </b> </td> <td> </td> </tr> <tr> <td> </td> <td> <b> Unextracted </b> </td> <td> <b> Extracted </b> </td> <td> <b> E/U <sup> b </sup> </b> </td> </tr> </thead> <tbody> <tr> <td> Normal </td> <td> 54 ± 6 </td> <td> 61 ± 4 </td> <td> 1.13 </td> </tr> <tr> <td> Axotomized </td> <td> 84 ± 8** </td> <td> 86 ± 9** </td> <td> 1.02 </td> </tr> </tbody> </table> </body> </html>

train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> Marker </b> </td> <td> <b> Species </b> </td> <td> <b> Working dilution </b> </td> <td> <b> Vendor or productor </b> </td> </tr> </thead> <tbody> <tr> <td colspan="4"> <b> Proliferation </b> </td> </tr> <tr> <td> BrdU </td> <td> Mouse IgG </td> <td> 1:500 </td> <td> Novo Castra (Newcastle, UK) </td> </tr> <tr> <td> BrdU </td> <td> Rat IgG </td> <td> 1:500 </td> <td> Accurate Chemicals (New York, USA) </td> </tr> <tr> <td colspan="4"> <b> Magnocellular neurons </b> </td> </tr> <tr> <td> OT </td> <td> Rabbit IgG </td> <td> 1:2000 </td> <td> Produced by G. Alonso </td> </tr> <tr> <td> VP </td> <td> Rabbit IgG </td> <td> 1:2000 </td> <td> Produced by G. Alonso </td> </tr> <tr> <td colspan="4"> <b> Astrocytes </b> </td> </tr> <tr> <td> GFAP </td> <td> Rabbit IgG </td> <td> 1:5000 </td> <td> Dakko (Glostrup, Denmark) </td> </tr> <tr> <td colspan="4"> <b> Microglia and endothelial cells </b> </td> </tr> <tr> <td> Lectin from bandeirae </td> <td> </td> <td> 1:2000 </td> <td> Sigma </td> </tr> <tr> <td> Simplifolia (IsoB4) </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td colspan="4"> <b> Oligodendrocyte progenitors </b> </td> </tr> <tr> <td> NG2 </td> <td> Rabbit IgG </td> <td> 1:500 </td> <td> Chemicon (Temecula, USA) </td> </tr> <tr> <td colspan="4"> <b> Vessels </b> </td> </tr> <tr> <td> Rat IgG-Alexa 488 conjugated </td> <td> Goat IgG </td> <td> 1:2000 </td> <td> Molecular Probes (Eugene, USA) </td> </tr> <tr> <td> EBA </td> <td> Mouse IGM </td> <td> 1:5000 </td> <td> Sternberger Monoclonals (Lutherville, USA) </td> </tr> <tr> <td> Nestin </td> <td> Mouse IgG </td> <td> 1:100 </td> <td> Hybridoma Bank (Iowa city, USA) </td> </tr> <tr> <td> Vimentin </td> <td> Mouse IgG </td> <td> 1:5000 </td> <td> Sigma </td> </tr> </tbody> </table> </body> </html>

train

330,474

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train

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> TOTAL NO PRESCRIPTIONS IN AREA OVER THE STUDY PERIOD </b> </td> <td> <b> NUMBER WITH ERRORS OF PRESCRIPTION WRITING </b> </td> <td> <b> NUMBER WITH DRUG ERRORS </b> </td> <td> <b> TOTAL NUMBER OF SCRIPTS WITH ERRORS </b> </td> <td> <b> % OF SCRIPTS WITH ERRORS </b> </td> </tr> </thead> <tbody> <tr> <td> OPD </td> <td> <b> 144 </b> </td> <td> <b> 64 </b> </td> <td> <b> 9 </b> </td> <td> <b> 73 </b> </td> <td> <b> 50% </b> </td> </tr> <tr> <td> A&E </td> <td> <b> 1117 </b> </td> <td> <b> 56 </b> </td> <td> <b> 4 </b> </td> <td> <b> 60 </b> </td> <td> <b> 5% </b> </td> </tr> <tr> <td> DAY </td> <td> <b> 561 </b> </td> <td> <b> 24 </b> </td> <td> <b> 2 </b> </td> <td> <b> 26 </b> </td> <td> <b> 5% </b> </td> </tr> <tr> <td> CASE </td> <td> </td> <td> </td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td> WARD </td> <td> <b> 130 </b> </td> <td> <b> 0 </b> </td> <td> <b> 0 </b> </td> <td> <b> 0 </b> </td> <td> <b> 0% </b> </td> </tr> <tr> <td> </td> <td> <b> 1952 </b> </td> <td> <b> 144 (7%) </b> </td> <td> <b> 15 (1%) </b> </td> <td> <b> 159 </b> </td> <td> <b> 8% </b> </td> </tr> </tbody> </table> </body> </html>

train

495,966

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> <b> GRADE OF DOCTOR </b> </td> <td> <b> ERRORS OF PRESCRIPTION WRITING </b> </td> <td> <b> DRUG RELATED ERRORS </b> </td> </tr> </thead> <tbody> <tr> <td> <b> SENIOR </b> </td> <td> 58 (46%) </td> <td> 0% </td> </tr> <tr> <td> <b> JUNIOR </b> </td> <td> 68 (54%) </td> <td> 15 (100%) </td> </tr> </tbody> </table> </body> </html>

train

392,421

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> <b> Ser </b> </td> <td> <b> Arg </b> </td> <td> <b> Total </b> </td> </tr> </thead> <tbody> <tr> <td> POAG </td> <td> 266 (95%) </td> <td> 14 (5%) </td> <td> 280 </td> </tr> <tr> <td> Controls </td> <td> 134 (91.8%) </td> <td> 12 (8.2%) </td> <td> 146 </td> </tr> <tr> <td> Total </td> <td> 400 </td> <td> 26 </td> <td> 426 </td> </tr> </tbody> </table> </body> </html>

train

95,508

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train

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train

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train

273,471

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318,912

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<html> <head> <meta charset="utf-8"/> <style> table, th, td { border: 1px solid black; font-size: 10px; } </style> </head> <body> <table frame="hsides" rules="groups" width="100%"> <thead> <tr> <td> </td> <td> </td> <td> <b> <i> P </i> Value </b> </td> <td> <b> OR </b> </td> <td colspan="2"> <b> 95% CI** </b> </td> </tr> </thead> <tbody> <tr> <td> <b> Smokers </b> </td> <td> Satisfied </td> <td> <i> 0.00* </i> </td> <td> 0.43 </td> <td> 0.35 </td> <td> 0.52 </td> </tr> <tr> <td> </td> <td> Dissatisfied </td> <td> <i> 0.00* </i> </td> <td> 2.48 </td> <td> 2.05 </td> <td> 3.00 </td> </tr> <tr> <td> </td> <td> Neither </td> <td> <i> 0.08 </i> </td> <td> 1.23 </td> <td> 0.97 </td> <td> 1.55 </td> </tr> </tbody> </table> </body> </html>